Puzanowska-Tarasiewicz Helena, Kuźmicka Ludmiła, Tarasiewicz Mirosław
Wyzsza Szkola Kosmetologii i Ochrony Zdrowia w Białymstoku, Zakład Nauk Chemicznych.
Pol Merkur Lekarski. 2009 Oct;27(160):338-40.
Reactive nitrogen species (RNS) and reactive oxygen species (ROS) are mainly free radicals which including non-paired electrons. They are constantly formed as side products of biological reactions. They are also generated directly and indirectly by the cells which were exposed to environmental stress, i.e., UV radiation, ionizing radiation, xenobioticts, light-absorbing compounds, e.g., porphyrines. These factors, which are a source of free radicals, initiate a significant signaling cascade inducing many changes in cells, such as cancerogenic transformation or cell death. Cells protect themselves against oxidative stress by means of antioxidative enzymes and compounds which in their structure have redox sensitive spots.
活性氮物质（RNS）和活性氧物质（ROS）主要是包含未成对电子的自由基。它们作为生物反应的副产物不断形成。它们也由暴露于环境应激（如紫外线辐射、电离辐射、外源性物质、吸光化合物，如卟啉）的细胞直接或间接产生。这些作为自由基来源的因素引发显著的信号级联反应，诱导细胞发生许多变化，如致癌转化或细胞死亡。细胞通过具有氧化还原敏感位点的抗氧化酶和化合物来保护自身免受氧化应激。
