[巴西帕拉州茹鲁蒂地区虫媒病毒血清学调查]
[Serological survey for arboviruses in Juruti, Pará State, Brazil].
作者信息
Cruz Ana Cecilia Ribeiro, Prazeres Assis do Socorro Correa dos, Gama Eliana Colares, Lima Maxwell Furtado de, Azevedo Raimunda do Socorro Silva, Casseb Lívia Medeiros Neves, Nunes Neto Joaquim Pinto, Martins Lívia Carício, Chiang Jannifer Oliveira, Rodrigues Sueli Guerreiro, Vasconcelos Pedro Fernando da Costa
机构信息
Seção de Arbovirologia e Febres Hemorrágicas, Instituto Evandro Chagas, Ananindeua, PA, Brazil.
出版信息
Cad Saude Publica. 2009 Nov;25(11):2517-23. doi: 10.1590/s0102-311x2009001100021.
This study aimed to measure the prevalence of antibodies to arboviruses in the area affected by the Juruti Project before local mining operations. A total of 1,597 human and 85 wild animal sera were examined, using the hemagglutination inhibition test against 19 antigens from the most prevalent arboviruses in the Brazilian Amazon and IgM-ELISA for dengue and yellow fever. Positive sera for Mayaro and Oropouche viruses were also tested by IgM-ELISA. Prevalence of hemagglutination inhibition antibodies to alphaviruses, flaviviruses, and orthobunyaviruses in humans was 28.7%, while for wild animals it was 8.2% for flaviviruses. Recent infections based on presence of IgM was confirmed for Mayaro (n = 5), Oropouche (n = 23), and dengue (n = 20). The results showed active circulation of the dengue, Mayaro, and Oropouche viruses in Juruti, as well as flaviviruses in wild animals, suggesting the circulation of these viruses in the Municipality of Juruti.
本研究旨在测量在朱鲁蒂项目影响地区进行当地采矿作业之前虫媒病毒抗体的流行情况。共检测了1597份人类血清和85份野生动物血清，采用血凝抑制试验检测针对巴西亚马逊地区最常见虫媒病毒的19种抗原，并用登革热和黄热病IgM-ELISA法进行检测。对马亚罗病毒和奥罗普切病毒的阳性血清也采用IgM-ELISA法进行检测。人类中对甲病毒、黄病毒和正布尼亚病毒血凝抑制抗体的流行率为28.7%，而野生动物中黄病毒的流行率为8.2%。基于IgM的存在，确认了马亚罗病毒（n = 5）、奥罗普切病毒（n = 23）和登革热病毒（n = 20）的近期感染情况。结果表明，登革热病毒、马亚罗病毒和奥罗普切病毒在朱鲁蒂地区活跃传播，野生动物中也存在黄病毒，这表明这些病毒在朱鲁蒂市传播。
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