Pei Qiuyan, Liang Meiying, Huang Xin, Wei Yanqiu
Department of Obstetric Ultrasonography, Peking University People's Hospital, Beijing 100044, China.
Pediatr Cardiol. 2010 Feb;31(2):234-7. doi: 10.1007/s00246-009-9596-x.
The objective of this study was to establish an anatomical atlas and a three-dimensional model of the fetal heart. To do this, we created a 60-microm cross-sectional image database of the heart of a Chinese male fetus. A 31-week stillborn fetus with no congenital defects was used as the model. All thoracic organs were removed from the thoracic cavity after formalin fixation and then frozen at -25 degrees C for 2 h. Frozen serial sections, 60-microm thick, were prepared and macroshot with a digital camera to obtain image data. Eight hundred seventy-one cross-sectional photos of the fetal heart were made at a resolution of 3888 x 2592 pixels. The atrioventricular cavity, as well as other fine structures, was revealed in the images, showing a clear boundary between the peripheral tissues. This rich database showing the three-dimensional features and anatomy of the fetal heart will be useful for teaching, scientific research, and clinical applications.
本研究的目的是建立胎儿心脏的解剖图谱和三维模型。为此，我们创建了一个中国男性胎儿心脏的60微米横截面图像数据库。使用一个无先天性缺陷的31周死产胎儿作为模型。在福尔马林固定后，将所有胸腔器官从胸腔中取出，然后在-25℃下冷冻2小时。制备60微米厚的冷冻连续切片，并用数码相机进行宏观拍摄以获取图像数据。以3888×2592像素的分辨率拍摄了871张胎儿心脏的横截面照片。图像中显示了房室腔以及其他精细结构，外周组织之间界限清晰。这个展示胎儿心脏三维特征和解剖结构的丰富数据库将有助于教学、科研和临床应用。
