Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, India.
Indian J Pediatr. 2010 Jan;77(1):61-5. doi: 10.1007/s12098-009-0263-2.
To study the role of sunlight exposure in determining the vitamin D status of underprivileged toddlers.
Height and weight were measured, clinical examination was performed, Food Frequency Questionnaire was administered and history of sunlight exposure was obtained in all (61) toddlers attending daytime crèche (Group B). Ionised calcium (iCa), inorganic Phosphorous (iP), alkaline phosphatase activity (ALP), serum parathyroid hormone (PTH) and 25 Hydroxy vitamin D (25OHD) were measured. Data were compared with results of a survey measuring similar parameters in 51 (of 251 eligible) toddlers from the same slum (Group A).
111 children (mean age 2.6 yr (0.7), boys 56) were studied. Prevalence of hypovitaminosis D was 77% in group B toddlers (46 of 60) and 16.4% (10 of 61) had rickets, while none of the group A toddlers had 25OHD levels below 30 nmol/L. Four children (7.8%) from Group A as against 24 (42.9%) from Group B, had sunshine exposure of < 30 minutes per day.
Underprivileged toddlers who were deprived of sunlight had a much greater incidence of hypovitaminosis D and frank rickets. The study has important public health implications and underscores the necessity for sunlight exposure in young children.
研究阳光暴露在决定贫困幼儿维生素 D 状况中的作用。
对所有（61 名）日间托儿所的幼儿（B 组）进行身高和体重测量、临床检查、食物频率问卷评估和阳光暴露史调查。检测离子钙（iCa）、无机磷（iP）、碱性磷酸酶活性（ALP）、血清甲状旁腺激素（PTH）和 25 羟维生素 D（25OHD）。将数据与来自同一贫民窟（A 组）的 51 名（251 名合格儿童中的 51 名）具有相似参数的儿童调查结果进行比较。
共研究了 111 名儿童（平均年龄 2.6 岁（0.7），男孩 56 名）。B 组幼儿（60 名中的 46 名）维生素 D 缺乏症的患病率为 77%，16.4%（61 名中的 10 名）患有佝偻病，而 A 组的儿童均无 25OHD 水平低于 30 nmol/L。A 组中有 4 名儿童（7.8%）每天接受的阳光照射时间少于 30 分钟，而 B 组中有 24 名儿童（42.9%）。
缺乏阳光照射的贫困幼儿维生素 D 缺乏症和佝偻病的发病率更高。该研究具有重要的公共卫生意义，强调了儿童接受阳光照射的必要性。
