抗性麦芽糊精对大鼠钙、镁、铁和锌表观吸收率的促进作用。
Promotive effects of resistant maltodextrin on apparent absorption of calcium, magnesium, iron and zinc in rats.
机构信息
Matsutani Chemical Industry Co., Ltd., Itami, Hyogo, Japan.
出版信息
Eur J Nutr. 2010 Apr;49(3):165-71. doi: 10.1007/s00394-009-0062-6.
BACKGROUND
It has been reported that low-viscous and fermentable dietary fiber and nondigestible oligosaccharides enhance mineral absorption. Resistant maltodextrin, nonviscous, fermentable and soluble source of dietary fiber, has several physiological functions. However, influence of resistant maltodextrin on mineral absorption is unclear.
AIM OF THE STUDY
We conducted balance studies in rats to investigate effects of resistant maltodextrin and hydrogenated resistant maltodextrin on apparent mineral absorption.
METHODS
In experiment 1 (Exp. 1), 40 rats were fed test diets based on AIN-93G with or without resistant maltodextrin or hydrogenated resistant maltodextrin for 2 weeks. In experiment 2 (Exp. 2), 32 rats were cecectomized (CX) or sham-operated (Sham) and fed diets with or without hydrogenated resistant maltodextrin for 1 week.
RESULTS
In Exp. 1, ingestion of resistant maltodextrin and hydrogenated resistant maltodextrin dose-dependently enhanced apparent absorption rates of Ca, Mg, Fe and Zn, and increased cecal fermentation with cecal expansion. In Exp. 2, the absorption rates of Ca and Mg were significantly enhanced by ingestion of hydrogenated resistant maltodextrin in Sham group but not in CX group. The promotion of Fe and Zn absorption was not affected by cecectomy.
CONCLUSION
Ingestion of resistant maltodextrin and hydrogenated resistant maltodextrin increased apparent Ca and Mg absorptions dependent on cecal fermentation, while other mechanisms may also be involved in promotion of apparent Fe and Zn absorption by resistant maltodextrin.
背景
据报道，低黏度和可发酵膳食纤维以及不可消化的低聚糖可促进矿物质吸收。抗性麦芽糊精是一种不可消化的、可发酵的、水溶性膳食纤维来源，具有多种生理功能。然而，抗性麦芽糊精对矿物质吸收的影响尚不清楚。
目的
我们在大鼠中进行了平衡研究，以调查抗性麦芽糊精和氢化抗性麦芽糊精对表观矿物质吸收的影响。
方法
在实验 1（Exp.1）中，40 只大鼠喂食基于 AIN-93G 的试验饮食，其中含有或不含有抗性麦芽糊精或氢化抗性麦芽糊精，为期 2 周。在实验 2（Exp.2）中，32 只大鼠接受盲肠切除术（CX）或假手术（Sham），并喂食含有或不含有氢化抗性麦芽糊精的饮食，为期 1 周。
结果
在 Exp.1 中，抗性麦芽糊精和氢化抗性麦芽糊精的摄入剂量依赖性地增加了 Ca、Mg、Fe 和 Zn 的表观吸收速率，并增加了盲肠发酵和盲肠扩张。在 Exp.2 中，Sham 组摄入氢化抗性麦芽糊精可显著提高 Ca 和 Mg 的吸收速率，但在 CX 组中则没有。盲肠切除术对 Fe 和 Zn 的吸收促进作用没有影响。
结论
摄入抗性麦芽糊精和氢化抗性麦芽糊精可增加依赖于盲肠发酵的表观 Ca 和 Mg 吸收，而其他机制也可能参与了抗性麦芽糊精对表观 Fe 和 Zn 吸收的促进作用。
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