First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Department of Pathology, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Eur J Orthop Surg Traumatol. 2023 May;33(4):773-778. doi: 10.1007/s00590-022-03256-5. Epub 2022 Mar 31.
Teratomas are a subtype of germ cell tumors composed of a variety of somatic tissues derived from more than one of the three germinal layers (ectoderm, endoderm and mesoderm). They can be classified as mature tumors and immature tumors. Teratomas most commonly arise at the sacrococcygeal region and the gonads. The occurrence of a teratoma outside the common gonadal and midline locations is exceptional. This review article lists the reported primary and metastatic malignant teratomas in extragonadal locations and discusses the possible explanation for the atypical location, their treatment and prognosis.
畸胎瘤是一种生殖细胞肿瘤,由来自三个胚层(外胚层、内胚层和中胚层)之一以上的多种体组织组成。它们可以分为成熟型和未成熟型。畸胎瘤最常发生在骶尾部和性腺。在常见的性腺和中线位置以外发生的畸胎瘤是罕见的。本文列出了报道的发生在性腺外部位的原发性和转移性恶性畸胎瘤,并讨论了这些非典型位置的可能解释、它们的治疗和预后。