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电话咨询能否改善早期乳腺癌幸存者的社会心理结局?

Can telephone counseling post-treatment improve psychosocial outcomes among early stage breast cancer survivors?

机构信息

AMC Cancer Research Center of the University of Colorado Cancer Center, University of Colorado, Denver, CO 80214, USA.

出版信息

Psychooncology. 2010 Sep;19(9):923-32. doi: 10.1002/pon.1653.

Abstract

OBJECTIVE

To determine whether a telephone counseling program can improve psychosocial outcomes among breast cancer patients post-treatment.

METHODS

A randomized trial was conducted involving 21 hospitals and medical centers, with assessments (self-administered questionnaires) at baseline, 12 and 18 months post-enrollment. Eligibility criteria included early stage diagnosis, enrollment during last treatment visit, and the ability to receive the intervention in English. Endpoints included distress (Impact of Event Scale), depression (Center for Epidemiologic Studies Depression Scale), and two study-specific measures: sexual dysfunction and personal growth. The control group (n=152) received a resource directory for breast cancer; the intervention group (n=152) also received a one-year, 16 session telephone counseling program augmented with additional print materials.

RESULTS

Significant intervention effects were found for sexual dysfunction at 12 (p=0.03) and 18 months (p=0.04) and personal growth (12 months: p=0.005; 18 months: p=0.03). No differences by group were found in mean scores for distress and depression, with both groups showing significant improvement at 12 and 18 months (all p values for within-group change from baseline were <or=0.003). However, when dichotomized at cutpoints suggestive of the need for a clinical referral, the control group showed virtually no change at 18 months, whereas the intervention group showed about a 50% reduction in both distress (p=0.07) and depression (p=0.06).

CONCLUSIONS

Telephone counseling may provide a viable method for extending psychosocial services to cancer survivors nationwide.

摘要

目的

确定电话咨询方案是否可以改善乳腺癌患者治疗后的心理社会结局。

方法

进行了一项随机试验,涉及 21 家医院和医疗中心,在基线、12 个月和 18 个月时进行评估(自我管理问卷)。入选标准包括早期诊断、在最后一次治疗就诊时入组、以及能够用英语接受干预。终点包括痛苦(事件影响量表)、抑郁(流行病学研究中心抑郁量表)和两项研究特定指标:性障碍和个人成长。对照组(n=152)接受乳腺癌资源目录;干预组(n=152)还接受为期一年、16 次的电话咨询方案,辅以额外的印刷材料。

结果

在 12 个月(p=0.03)和 18 个月(p=0.04)时发现性障碍存在显著的干预效果,在 12 个月(p=0.005)和 18 个月(p=0.03)时发现个人成长存在显著的干预效果。两组的痛苦和抑郁的平均评分均无差异,两组在 12 个月和 18 个月时均显示出显著的改善(组内从基线变化的所有 p 值均<0.003)。然而,当以提示需要临床转诊的切点进行二分法划分时,对照组在 18 个月时几乎没有变化,而干预组在痛苦(p=0.07)和抑郁(p=0.06)方面均降低了约 50%。

结论

电话咨询可能为向全国范围内的癌症幸存者提供心理社会服务提供了一种可行的方法。

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