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同伴提供的电话干预对乳腺癌复发女性的影响。

Impact of a peer-delivered telephone intervention for women experiencing a breast cancer recurrence.

作者信息

Gotay Carolyn Cook, Moinpour Carol M, Unger Joseph M, Jiang Caroline S, Coleman Dorothy, Martino Silvana, Parker Beverly J, Bearden James D, Dakhil Shaker, Gross Howard M, Lippman Scott, Albain Kathy S

机构信息

Cancer Research Center of Hawaii, Honolulu, HI 96822, USA.

出版信息

J Clin Oncol. 2007 May 20;25(15):2093-9. doi: 10.1200/JCO.2006.07.4674.

DOI:10.1200/JCO.2006.07.4674
PMID:17513815
Abstract

PURPOSE

A first breast cancer recurrence creates considerable distress, yet few psychosocial interventions directed at this population have been reported. The Southwest Oncology Group conducted a phase III randomized trial to evaluate the effectiveness of a brief telephone intervention.

PATIENTS AND METHODS

Three hundred five women experiencing a first recurrence of breast cancer were randomly assigned to standard care or intervention. The intervention consisted of four to eight telephone calls delivered over a 1-month period. The calls were conducted by trained peer counselors at a breast cancer advocacy organization, the Y-ME National Breast Cancer Organization, and followed a standard curriculum. Psychosocial distress (Cancer Rehabilitation Evaluation System-Short Form [CARES-SF]) and depressive symptoms (Center for Epidemiologic Studies Depression Scale [CES-D]) outcomes were assessed at baseline and 3 and 6 months. The 3-month assessment was the primary end point and is the focus of this article.

RESULTS

Analysis revealed no differences in distress or depressive symptoms at 3 months between the intervention and control groups; at 3 months, 70% of control patients and 66% of intervention patients reported psychosocial distress, and 40% of control patients and 47% of intervention patients exhibited depressive symptoms.

CONCLUSION

Telephone peer counseling did not lead to better psychosocial outcomes. The persistent distress in these women supports the urgent need for the development and testing of more intensive or different supportive interventions for this group of patients.

摘要

目的

首次乳腺癌复发会造成相当大的痛苦,但针对这一人群的心理社会干预措施报道较少。西南肿瘤协作组开展了一项III期随机试验,以评估简短电话干预的效果。

患者与方法

305名首次出现乳腺癌复发的女性被随机分配至标准护理组或干预组。干预措施包括在1个月内进行4至8次电话沟通。这些电话由乳腺癌宣传组织Y-ME全国乳腺癌组织中经过培训的同伴咨询师拨打,并遵循标准课程。在基线、3个月和6个月时评估心理社会痛苦(癌症康复评估系统简表[CARES-SF])和抑郁症状(流行病学研究中心抑郁量表[CES-D])结果。3个月时的评估是主要终点,也是本文的重点。

结果

分析显示,干预组和对照组在3个月时的痛苦或抑郁症状无差异;3个月时,70%的对照组患者和66%的干预组患者报告有心理社会痛苦,40%的对照组患者和47%的干预组患者有抑郁症状。

结论

同伴电话咨询并未带来更好的心理社会结局。这些女性持续存在的痛苦表明,迫切需要为这组患者开发和测试更强化或不同的支持性干预措施。

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