胃肠道出血：卡维地洛——一级预防的最佳β受体阻滞剂？ - Suppr

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Gastrointestinal bleeding: Carvedilol-the best beta-blocker for primary prophylaxis?

作者信息

Tsochatzis Emmanuel A, Triantos Christos K, Burroughs Andrew K

出版信息

Nat Rev Gastroenterol Hepatol. 2009 Dec;6(12):692-4. doi: 10.1038/nrgastro.2009.198.

DOI:10.1038/nrgastro.2009.198

PMID:19946301

Abstract

摘要

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引用本文的文献

Carvedilol versus traditional, non-selective beta-blockers for adults with cirrhosis and gastroesophageal varices.卡维地洛与传统非选择性β受体阻滞剂用于肝硬化合并食管胃静脉曲张的成人患者比较

Cochrane Database Syst Rev. 2018 Oct 29;10(10):CD011510. doi: 10.1002/14651858.CD011510.pub2.

The effect of carvedilol and propranolol on portal hypertension in patients with cirrhosis: a meta-analysis.卡维地洛与普萘洛尔对肝硬化患者门静脉高压的影响：一项荟萃分析。

Patient Prefer Adherence. 2015 Jul 14;9:961-70. doi: 10.2147/PPA.S84762. eCollection 2015.

Is it time to replace propranolol with carvedilol for portal hypertension?是时候将普萘洛尔换成卡维地洛来治疗门静脉高压症了吗？

World J Gastrointest Endosc. 2015 May 16;7(5):532-9. doi: 10.4253/wjge.v7.i5.532.

Management of varices in patients with cirrhosis.肝硬化患者静脉曲张的处理。

Nat Rev Gastroenterol Hepatol. 2013 Jul;10(7):402-12. doi: 10.1038/nrgastro.2013.51. Epub 2013 Apr 2.

Endoscopic management of esophageal varices.食管静脉曲张的内镜治疗

World J Gastrointest Endosc. 2012 Jul 16;4(7):312-22. doi: 10.4253/wjge.v4.i7.312.

Primary prevention of variceal hemorrhage.静脉曲张出血的一级预防。

Curr Gastroenterol Rep. 2011 Feb;13(1):3-9. doi: 10.1007/s11894-010-0160-x.

本文引用的文献

Hepatology. 2009 Sep;50(3):825-33. doi: 10.1002/hep.23045.

beta-Blockers protect against spontaneous bacterial peritonitis in cirrhotic patients: a meta-analysis.β受体阻滞剂可预防肝硬化患者自发性细菌性腹膜炎：一项荟萃分析。

Liver Int. 2009 Sep;29(8):1189-93. doi: 10.1111/j.1478-3231.2009.02038.x. Epub 2009 May 1.

Banding ligation versus beta-blockers as primary prophylaxis in esophageal varices: systematic review of randomized trials.内镜下套扎术与β受体阻滞剂作为食管静脉曲张一级预防措施的比较：随机试验的系统评价

Am J Gastroenterol. 2007 Dec;102(12):2842-8; quiz 2841, 2849. doi: 10.1111/j.1572-0241.2007.01564.x.

Effect of carvedilol on portal hypertension depends on the degree of endothelial activation and inflammatory changes.卡维地洛对门静脉高压的影响取决于内皮激活程度和炎症变化。

Scand J Gastroenterol. 2006 Dec;41(12):1454-63. doi: 10.1080/00365520600780403.

Hepatic vein pressure gradient reduction and prevention of variceal bleeding in cirrhosis: a systematic review.肝静脉压力梯度降低与肝硬化患者静脉曲张出血的预防：一项系统评价

Gastroenterology. 2006 Nov;131(5):1611-24. doi: 10.1053/j.gastro.2006.09.013.

Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis.长期服用卡维地洛与普萘洛尔治疗肝硬化门静脉高压症的随机对照研究

Hepatology. 2002 Dec;36(6):1367-73. doi: 10.1053/jhep.2002.36947.

Haemodynamic effects of acute and chronic administration of low-dose carvedilol, a vasodilating beta-blocker, in patients with cirrhosis and portal hypertension.低剂量卡维地洛（一种血管舒张性β受体阻滞剂）急性和慢性给药对肝硬化和门静脉高压患者的血流动力学影响。

Aliment Pharmacol Ther. 2002 Mar;16(3):373-80. doi: 10.1046/j.1365-2036.2002.01190.x.

Improving prognosis following a first variceal haemorrhage over four decades.四十多年来首次静脉曲张出血后的预后改善情况。

Gut. 2001 Nov;49(5):682-5. doi: 10.1136/gut.49.5.682.

Acute and chronic haemodynamic and renal effects of carvedilol in patients with cirrhosis.

J Hepatol. 1999 Mar;30(3):479-84. doi: 10.1016/s0168-8278(99)80108-1.

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