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从黄兰花属植物中提取的胃保护黄酮类成分

Gastroprotective flavonoid constituents from Oroxylum indicum Vent.

机构信息

Natural Products Laboratory, Organic Division-I, Indian Institute of Chemical Technology, Hyderabad 500 607, India.

出版信息

Bioorg Med Chem Lett. 2010 Jan 1;20(1):117-20. doi: 10.1016/j.bmcl.2009.11.024. Epub 2009 Nov 12.

DOI:10.1016/j.bmcl.2009.11.024
PMID:19948405
Abstract

Chemical investigation of the stem bark of Oroxylum indicum resulted in the isolation and characterization of two new flavonoid glycosides (1, 2), along with seven known compounds (3-9). Their structures were established on the basis of extensive spectroscopic (IR, MS, 2D NMR) data analysis and by the comparison with spectroscopic data reported in the literature. In addition, all the compounds were tested for their ulcer protective effects against various gastric ulceritis inducing models in rats.

摘要

从黄粱木的茎皮中分离得到两个新的黄酮苷(1,2)和七个已知化合物(3-9)。通过广泛的光谱(IR、MS、2D NMR)数据分析和与文献报道的光谱数据比较,确定了它们的结构。此外,还测试了所有化合物对大鼠各种胃溃疡诱导模型的溃疡保护作用。

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