Department of Surgery, Krankenhaus Ludwigsburg, Germany.
Eur J Med Res. 2009 Nov 3;14(11):480-6. doi: 10.1186/2047-783x-14-11-280.
Today, the biomechanical fundamentals of skin expansion are based on viscoelastic models of the skin. Although many studies have been conducted in vitro, analyses performed in vivo are rare. Here, we present in vivo measurements of the expansion at the skin surface as well as measurement of the corresponding intracutaneous oxygen partial pressure. In our study the average skin stretching was 24%, with a standard deviation of 11%, excluding age or gender dependency. The measurement of intracutaneous oxygen partial pressure produced strong inter-individual fluctuations, including initial values at the beginning of the measurement, as well as varying individual patient reactions to expansion of the skin. Taken together, we propose that even large defect wounds can be closed successfully using the mass displacement caused by expansion especially in areas where soft, voluminous tissue layers are present.
如今，皮肤扩张的生物力学基础是基于皮肤的黏弹性模型。尽管已经进行了许多体外研究，但体内分析却很少。在这里，我们展示了皮肤表面扩张的体内测量以及相应的皮内氧分压测量。在我们的研究中，平均皮肤拉伸率为 24%，标准差为 11%，不包括年龄或性别依赖性。皮内氧分压的测量产生了强烈的个体间波动，包括测量开始时的初始值，以及个体患者对皮肤扩张的不同反应。总之，我们提出，即使是大面积的缺损伤口，也可以通过扩张引起的质量位移成功闭合，特别是在存在柔软、大量组织层的区域。
