Schulmeister Lisa
Clin J Oncol Nurs. 2009 Dec;13(6):711-4. doi: 10.1188/09.CJON.711-714.
Transdermal medication delivery systems provide systemic therapy by passive diffusion through the skin. They offer an alternative route of medication administration and may be well suited for patients who are unable to take or retain oral medications. Granisetron transdermal system (Sancuso(R), ProStrakan, Inc.) is the first transdermal medication patch indicated for the prevention of nausea and vomiting in patients receiving moderately or highly emetogenic chemotherapy. As with all transdermal medications, safety considerations exist with respect to storing, handling, applying, and disposing of the granisetron transdermal system. Oncology nurses should be aware of new developments in the management of chemotherapy-induced nausea and vomiting and knowledgeable about transdermal medication delivery.
透皮给药系统通过皮肤的被动扩散提供全身治疗。它们提供了一种替代的给药途径，可能非常适合那些无法服用或保留口服药物的患者。格拉司琼透皮系统（Sancuso(R)，ProStrakan公司）是首个被批准用于预防接受中度或高度致吐性化疗患者恶心和呕吐的透皮给药贴剂。与所有透皮药物一样，在格拉司琼透皮系统的储存、处理、应用和处置方面存在安全考量。肿瘤学护士应了解化疗引起的恶心和呕吐管理方面的新进展，并熟悉透皮给药。
