Hanson Mark D, Zuker Ronald M, Shaul Randi Zlotnik
The Hospital for Sick Children, Toronto, Ontario.
Can J Plast Surg. 2008 Winter;16(4):205-10. doi: 10.1177/229255030801600407.
Current pediatric burn care has resulted in survival being the expectation for most children. Composite tissue allotransplantation in the form of face or hand transplantation may present opportunities for reconstructive surgery of patients with burns. The present paper addresses the question "Could facial transplantation be of therapeutic benefit in the treatment of pediatric burns associated with facial disfigurement?"
Therapeutic benefit of facial transplantation was defined in terms of psychiatric adjustment and quality of life (QOL). To ascertain therapeutic benefit, studies of pediatric burn injury and associated psychiatric adjustment and QOL in children, adolescents and adults with pediatric burns, were reviewed.
Pediatric burn injury is associated with anxiety disorders, including post-traumatic stress disorder and depressive disorders. Many patients with pediatric burns do not routinely access psychiatric care for these disorders, including those for psychiatric assessment of suicidal risk. A range of QOL outcomes were reported; four were predominantly satisfactory and one was predominantly unsatisfactory.
Facial transplantation may reduce the risk of depressive and anxiety disorders other than post-traumatic stress disorder. Facial transplantation promises to be the new reconstructive psychosurgery, because it may be a surgical intervention with the potential to reduce the psychiatric suffering associated with pediatric burns. Furthermore, patients with pediatric burns may experience the stigma of disfigurement and psychiatric conditions. The potential for improved appearance with facial transplantation may reduce this 'dual stigmata'. Studies combining surgical and psychiatric research are warranted.
当前的小儿烧伤护理使大多数儿童有望存活。面部或手部移植形式的复合组织同种异体移植可能为烧伤患者的重建手术带来机会。本文探讨“面部移植对治疗伴有面部毁容的小儿烧伤是否具有治疗益处?”这一问题。
面部移植的治疗益处依据心理调适和生活质量(QOL)来定义。为确定治疗益处,对小儿烧伤以及小儿烧伤患儿、青少年和成人的相关心理调适和生活质量的研究进行了综述。
小儿烧伤与焦虑症相关,包括创伤后应激障碍和抑郁症。许多小儿烧伤患者并未常规接受针对这些病症的精神科护理,包括那些针对自杀风险进行精神科评估的患者。报告了一系列生活质量结果;四项主要是令人满意的,一项主要是不令人满意的。
面部移植可能会降低除创伤后应激障碍之外的抑郁和焦虑症风险。面部移植有望成为新的重建性精神外科手术,因为它可能是一种具有降低与小儿烧伤相关的精神痛苦潜力的外科干预措施。此外,小儿烧伤患者可能会遭受毁容和精神状况带来的耻辱感。面部移植改善外观的潜力可能会减少这种“双重耻辱”。有必要开展结合外科和精神科研究的项目。