Muñoz-Velez Daniel, Garcia-Montes Fernando, Costa-Bauza Antonia, Grases Felix
Department of Urology, University Hospital Son Dureta, C/Andrea Doria, 55, 07013, Palma de Mallorca, Spain.
Urol Res. 2010 Feb;38(1):35-9. doi: 10.1007/s00240-009-0230-4. Epub 2009 Dec 1.
Most studies on epidemiology, composition, and recurrence of renal calculi include both spontaneously passed calculi and those retrieved after surgical manipulation or shock wave lithotripsy. The present study exclusively focused on epidemiology, composition, and recurrence of spontaneously expelled stones in patients from North and East Mallorca (Spain) which represents a geographically specific non-urban region of a developed country. The study involved 136 patients who spontaneously passed 205 renal calculi. All calculi were classified and sub-classified according to composition after macroscopic and microscopic examination. We also analyzed prevalence, gender, age, and stone recurrence rate over a period of 3 years. The peak incidence of spontaneously stone passage is within the fourth to sixth decade. Overall male to female ratio was 3/1. Calcium oxalate was the most prevalent composition (64.8%) followed by uric acid (25.3%), mixed stones (5.3%) and calcium phosphate calculi (4.3%). Uric acid stones were the most recurrent (50%) followed by calcium oxalate monohydrate papillary calculi (26.4%), calcium oxalate monohydrate un-attached calculi (19.2%), calcium oxalate dihydrate calculi (18.3%), calcium phosphate calculi (14%), and mixed calculi (12.5%). In conclusion, spontaneously passed stones in Mallorcan population have similar epidemiology, composition, and recurrence rate from that found in other developed countries. Calcium oxalate stones are largely the most spontaneously passed type of calculi and uric acid stones are the most frequently recurred. These findings are also found to be similar to those reported in previous studies examining both spontaneously and non-spontaneously passed stones.
大多数关于肾结石的流行病学、成分和复发情况的研究,既包括自然排出的结石,也包括手术取出或经冲击波碎石术后取出的结石。本研究专门聚焦于西班牙马略卡岛北部和东部地区患者自然排出结石的流行病学、成分和复发情况,该地区代表了一个发达国家中地理上特定的非城市区域。该研究涉及136例自然排出205颗肾结石的患者。所有结石在经过宏观和微观检查后,根据成分进行分类和再分类。我们还分析了3年内的患病率、性别、年龄和结石复发率。自然排石的高峰发病率在40至60岁之间。总体男女比例为3比1。草酸钙是最常见的成分(64.8%),其次是尿酸(25.3%)、混合性结石(5.3%)和磷酸钙结石(4.3%)。尿酸结石复发率最高(50%),其次是一水草酸钙乳头状结石(26.4%)、一水草酸钙游离结石(19.2%)、二水草酸钙结石(18.3%)、磷酸钙结石(14%)和混合性结石(12.5%)。总之,马略卡岛人群中自然排出的结石在流行病学、成分和复发率方面与其他发达国家相似。草酸钙结石在很大程度上是最常自然排出的结石类型,而尿酸结石复发频率最高。这些发现也与之前关于自然排出和非自然排出结石的研究报告相似。