Moshy Jeremiah Robert, Sohala Karpal Singh, Sebasaza Fredrick M, Berege Gemma
Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Muhimbili National Hospital, Dar es Salaam, Tanzania.
East Afr Health Res J. 2024;8(2):195-199. doi: 10.24248/eahrj.v8i2.781. Epub 2024 Jun 26.
Pleomorphic adenoma (PA) is the most common benign tumor representing about 80% of all salivary gland tumors. Despite this, there is limited documentation of the demographic information and pattern of PA in Tanzania. This study retrospectively determines the demographic information and the pattern of presentation of pleomorphic adenomas of the salivary gland among patients managed at a tertiary hospital in Tanzania.
This was a retrospective study of histological results of salivary gland pleomorphic adenoma diagnosed between 2016 and 2021. The information gathered included the age and sex of the patient and the anatomical location. Data analysis was done using Statistical Package for the Social Sciences version 27 computer program.
Out of 1824 reports of patients with oral and maxillofacial lesions retrieved from the archives of the department, 62 (3.4%) had the diagnosis of pleomorphic adenoma of the salivary glands. The patients' ages at diagnosis ranged from 7 to 72 years, with a mean age of 39.9 (SEM = 2.3) years. The male-to-female ratio of patients diagnosed with pleomorphic adenoma was 1:1. There were 31 (50%) cases of pleomorphic adenomas affecting major salivary glands. The palatal minor salivary glands were the most (n=31, 50%) affected followed by the parotid gland (n=16, 25.8%).
Pleomorphic adenomas have no sex predilection, most of these lesions occur during the 3 to 5 decade of life. The majority of pleomorphic adenomas occur in the palatal minor salivary glands.
多形性腺瘤（PA）是最常见的良性肿瘤，约占所有涎腺肿瘤的80%。尽管如此，坦桑尼亚关于PA的人口统计学信息和发病模式的文献有限。本研究回顾性地确定了坦桑尼亚一家三级医院收治的患者中涎腺多形性腺瘤的人口统计学信息和临床表现模式。
这是一项对2016年至2021年间诊断的涎腺多形性腺瘤组织学结果的回顾性研究。收集的信息包括患者的年龄、性别和解剖位置。使用社会科学统计软件包第27版计算机程序进行数据分析。
从该科室档案中检索到1824份口腔颌面病变患者报告，其中62例（3.4%）诊断为涎腺多形性腺瘤。诊断时患者年龄在7岁至72岁之间，平均年龄为39.9（标准误=2.3）岁。诊断为多形性腺瘤的患者男女比例为1:1。有31例（50%）多形性腺瘤累及大涎腺。腭部小涎腺受累最多（n=31，50%），其次是腮腺（n=16，25.8%）。
多形性腺瘤无性别倾向，这些病变大多发生在30至50岁之间。大多数多形性腺瘤发生在腭部小涎腺。
