Kim Ji Seok, Ha Wi Ho, Jeong Jong Hwi, Cho Kun-Woo, Lee Jai Ki
Korea Atomic Energy Research Institute, Daejeon, Korea.
Radiat Prot Dosimetry. 2010 Feb;138(2):119-22. doi: 10.1093/rpd/ncp215. Epub 2009 Dec 1.
Quantification of radioactivity in the body by in vivo bioassay uses counting efficiencies obtained from calibration from a phantom. Usually a standardised BOMAB (Bottle Manikin Absorption) phantom is employed for whole-body counting. The physical size of workers being counted, however, may differ from the calibration phantom, and can be a source of significant errors in dose estimates. A methodology was developed applying subject-specific efficiency data determined by Monte Carlo simulation based on a voxel phantom that was constructed from photographic images of the subject. This approach was demonstrated using a BOMAB phantom. The measured and calculated efficiencies agreed well, with maximum deviation of 30 % at 1.836 MeV (Y-88 gamma-rays). The expected counting efficiencies for an obese volunteer appear higher compared with a BOMAB phantom. This is caused by a closer distance between the detector and the body surface. The fast construction technique of voxel phantoms will contribute to a reduction in uncertainty caused by variations in the counting geometry.
通过体内生物测定法对体内放射性进行定量时,使用从体模校准获得的计数效率。通常采用标准化的BOMAB(人体模型吸收)体模进行全身计数。然而,被计数工人的身体尺寸可能与校准体模不同,这可能是剂量估计中显著误差的一个来源。开发了一种方法,应用基于由受试者的摄影图像构建的体素体模通过蒙特卡罗模拟确定的特定受试者效率数据。使用BOMAB体模展示了这种方法。测量效率和计算效率吻合良好,在1.836兆电子伏(Y-88伽马射线)处最大偏差为30%。与BOMAB体模相比,肥胖志愿者的预期计数效率似乎更高。这是由于探测器与身体表面之间的距离更近。体素体模的快速构建技术将有助于减少由计数几何形状变化引起的不确定性。