砜连接的双杂环——吡唑基恶二唑和吡唑基噻二唑的合成、抗菌及抗氧化活性
Synthesis, antimicrobial and antioxidant activities of sulfone linked bis heterocycles-pyrazolyl oxadiazoles and pyrazolyl thiadiazole.
作者信息
Padmavathi Venkatapuram, Reddy Sanapalli Nagi, Mahesh Konda
机构信息
Department of Chemistry, Sri Venkateswara University, Tirupati, India.
出版信息
Chem Pharm Bull (Tokyo). 2009 Dec;57(12):1376-80. doi: 10.1248/cpb.57.1376.
PMID:19952447
Abstract
A new class of bis heterocycles-sulfone linked pyrazolyl oxadiazoles and thiadiazoles were developed from Z-styrylsulfonylacetic acid. The pyrazolyl thiadiazoles exhibited excellent antimicrobial activity whereas pyrazolyl oxadiazoles displayed good antioxidant activity.
摘要
一类新型的双杂环化合物——砜连接的吡唑基恶二唑和噻二唑由Z-苯乙烯基磺酰基乙酸合成。吡唑基噻二唑表现出优异的抗菌活性，而吡唑基恶二唑则显示出良好的抗氧化活性。
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