Streker M, Reuther T, Verst S, Kerscher M
Studiengang Kosmetikwissenschaft (FB 13), Universität Hamburg.
Hautarzt. 2010 Feb;61(2):139-44. doi: 10.1007/s00105-009-1841-y.
The purpose of this study was to evaluate the efficacy and tolerability of aluminium chloride gel for treatment of axillary hyperhidrosis.
A total of 20 patients aged 22-38 (mean age: 26.9+/-4.3) with idiopathic axillary hyperhidrosis were included and treated with an antiperspirant (Sweat-off, Sweat-off GmbH, Hügelsheim). Study duration was 42 days. Treatment efficacy was evaluated clinically, as well as by starch-iodine test, gravimetric analysis and evaluation of the skin surface pH.
After treatment there was a significant clinical improvement accompanied by significant qualitative and quantitative reduction of sweat as well as a significant reduction of skin surface pH. Except for slight skin irritation in 6 patients, there were no other side effects. Patient satisfaction improved markedly during the study.
Treatment of axillary hyperhidrosis with aluminium chloride is an effective, safe and inexpensive treatment modality.
本研究旨在评估氯化铝凝胶治疗腋窝多汗症的疗效和耐受性。
共纳入20例年龄在22 - 38岁（平均年龄：26.9±4.3）的特发性腋窝多汗症患者，使用一种止汗剂（Sweat-off，Sweat-off GmbH，许格尔斯海姆）进行治疗。研究持续时间为42天。通过临床评估、淀粉碘试验、重量分析以及皮肤表面pH值评估来评价治疗效果。
治疗后临床症状有显著改善，同时汗液的质和量均显著减少，皮肤表面pH值也显著降低。除6例患者有轻微皮肤刺激外，无其他副作用。在研究过程中患者满意度明显提高。
用氯化铝治疗腋窝多汗症是一种有效、安全且廉价的治疗方式。
