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[腋窝多汗症——氯化铝止汗剂的疗效和耐受性。对20例特发性腋窝多汗症患者的前瞻性评估]

[Axillary hyperhidrosis--efficacy and tolerability of an aluminium chloride antiperspirant. Prospective evaluation on 20 patients with idiopathic axillary hyperhidrosis].

作者信息

Streker M, Reuther T, Verst S, Kerscher M

机构信息

Studiengang Kosmetikwissenschaft (FB 13), Universität Hamburg.

出版信息

Hautarzt. 2010 Feb;61(2):139-44. doi: 10.1007/s00105-009-1841-y.

Abstract

BACKGROUND

The purpose of this study was to evaluate the efficacy and tolerability of aluminium chloride gel for treatment of axillary hyperhidrosis.

PATIENTS AND METHODS

A total of 20 patients aged 22-38 (mean age: 26.9+/-4.3) with idiopathic axillary hyperhidrosis were included and treated with an antiperspirant (Sweat-off, Sweat-off GmbH, Hügelsheim). Study duration was 42 days. Treatment efficacy was evaluated clinically, as well as by starch-iodine test, gravimetric analysis and evaluation of the skin surface pH.

RESULTS

After treatment there was a significant clinical improvement accompanied by significant qualitative and quantitative reduction of sweat as well as a significant reduction of skin surface pH. Except for slight skin irritation in 6 patients, there were no other side effects. Patient satisfaction improved markedly during the study.

CONCLUSION

Treatment of axillary hyperhidrosis with aluminium chloride is an effective, safe and inexpensive treatment modality.

摘要

背景

本研究旨在评估氯化铝凝胶治疗腋窝多汗症的疗效和耐受性。

患者与方法

共纳入20例年龄在22 - 38岁(平均年龄:26.9±4.3)的特发性腋窝多汗症患者,使用一种止汗剂(Sweat-off,Sweat-off GmbH,许格尔斯海姆)进行治疗。研究持续时间为42天。通过临床评估、淀粉碘试验、重量分析以及皮肤表面pH值评估来评价治疗效果。

结果

治疗后临床症状有显著改善,同时汗液的质和量均显著减少,皮肤表面pH值也显著降低。除6例患者有轻微皮肤刺激外,无其他副作用。在研究过程中患者满意度明显提高。

结论

用氯化铝治疗腋窝多汗症是一种有效、安全且廉价的治疗方式。

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