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评估早期声门上型癌症的现有手术治疗选择。

Evaluation of available surgical management options for early supraglottic cancer.

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, University of Erlangen - Nuremberg Medical School, Erlangen, Germany.

出版信息

Head Neck. 2010 Aug;32(8):1048-55. doi: 10.1002/hed.21289.

Abstract

BACKGROUND

This study was undertaken to evaluate the oncologic results of endoscopic and open surgical techniques in early supraglottic cancer.

METHODS

We performed a retrospective evaluation of 101 patients surgically treated for stage I or II supraglottic carcinomas. Laser surgery, horizontal laryngectomy, and total laryngectomy were compared for disease-specific survival and local control rates. Surgical techniques were additionally compared for incidence of major complications, related tracheotomies, and swallowing function retention.

RESULTS

No statistically significant differences were noted among the different types of procedures regarding disease-specific survival and local control. A lower incidence of major complications, permanent gastrostomies, and significantly lower incidence of tracheotomies were noted for laser surgery compared with open techniques.

CONCLUSION

Larynx-preserving surgical modalities offer comparable oncologic results with total laryngectomy in early supraglottic cancer. In addition, laser surgery has a lower incidence of complications and better functional results compared with open partial or total laryngectomy.

摘要

背景

本研究旨在评估早期声门上型癌的内镜和开放手术技术的肿瘤学结果。

方法

我们对 101 例接受 I 期或 II 期声门上型癌手术治疗的患者进行了回顾性评估。比较了激光手术、水平喉切除术和全喉切除术在疾病特异性生存率和局部控制率方面的差异。此外,还比较了手术技术在主要并发症、相关气管切开术和吞咽功能保留方面的发生率。

结果

不同手术类型在疾病特异性生存率和局部控制方面无统计学差异。与开放技术相比,激光手术的主要并发症、永久性胃造口术和气管切开术的发生率明显更低。

结论

在早期声门上型癌中,保留喉的手术方式与全喉切除术具有相当的肿瘤学结果。此外,与开放的部分或全喉切除术相比,激光手术的并发症发生率更低,功能结果更好。

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