Center for Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA.
Adv Drug Deliv Rev. 2010 Mar 18;62(4-5):449-57. doi: 10.1016/j.addr.2009.11.016. Epub 2009 Nov 30.
Nano/Microfluidic technologies are emerging as powerful enabling tools for diagnosis and monitoring of infectious diseases in both developed and developing countries. Miniaturized nano/microfluidic platforms that precisely manipulate small fluid volumes can be used to enable medical diagnosis in a more rapid and accurate manner. In particular, these nano/microfluidic diagnostic technologies are potentially applicable to global health applications, since they are disposable, inexpensive, portable, and easy-to-use for detection of infectious diseases. In this paper, we review recent advances in nano/microfluidic technologies for clinical point-of-care applications at resource-limited settings in developing countries.
纳米/微流控技术正在成为发达国家和发展中国家诊断和监测传染病的有力工具。微型化的纳米/微流控平台可以精确地操控小体积的流体，从而能够更快速、更准确地进行医疗诊断。特别是，这些纳米/微流控诊断技术可能适用于全球卫生应用，因为它们是一次性的、廉价的、便携式的，并且易于用于传染病的检测。在本文中，我们综述了在发展中国家资源有限的环境下，用于临床即时检测应用的纳米/微流控技术的最新进展。
