Children's Hospital Boston, Boston MA 02115, USA.
Nutr Clin Pract. 2009 Dec;24(6):709-17. doi: 10.1177/0884533609351318.
Peripheral parenteral nutrition (PPN) is often viewed as the stepchild of parenteral nutrition (PN) infused via a central venous catheter. Anecdotal reports suggest that there has been increased interest in PPN in the United States and even more so in Europe because of improvements in catheter design and infusion technology, both of which have the potential to decrease complications such as infusion phlebitis. PPN, like PN via a central venous catheter, contains dextrose, amino acids, electrolytes, vitamins, and minerals, but in more limited capacity. One of the perceived benefits of PPN is the relative ease in establishing peripheral access, which may prevent delays in establishing nutrition support. PPN is intended for short-term use or supplementation. In most instances, it is used to maintain a previously well-nourished, nonhypermetabolic patient or to serve as a bridge to centrally administered infusions or enteral feedings until more suitable nutrition can be provided. In some cases, inappropriate use may result in infusion phlebitis or inadequate nutrient intake. Conflicting recommendations from various organizations further complicate and confuse prescribers. The intent of this review is to discuss PPN and the challenges its use presents to the practitioner.
外周肠外营养（PPN）常被视为经中心静脉导管输注的肠外营养（PN）的“弃儿”。传闻表明，由于导管设计和输注技术的改进，美国甚至欧洲对 PPN 的兴趣有所增加，因为这两者都有可能降低输注静脉炎等并发症的风险。PPN 与经中心静脉导管的 PN 一样，含有葡萄糖、氨基酸、电解质、维生素和矿物质，但容量较小。PPN 的一个被认为的好处是相对容易建立外周通路，这可能会避免在建立营养支持方面的延迟。PPN 旨在短期使用或补充。在大多数情况下，它用于维持营养状况良好、代谢不亢进的患者，或作为桥接，以进行中心输注或肠内喂养，直到可以提供更合适的营养。在某些情况下，不适当的使用可能导致输注静脉炎或营养摄入不足。来自不同组织的相互矛盾的建议进一步使医生感到困惑。本综述的目的是讨论 PPN 及其使用给临床医生带来的挑战。
