RNA-silencing enzymes Pol IV and Pol V in maize: more than one flavor?
作者信息
Pikaard Craig S, Tucker Sarah
机构信息
Department of Biology, Indiana University, Bloomington, Indiana, USA.
出版信息
PLoS Genet. 2009 Nov;5(11):e1000736. doi: 10.1371/journal.pgen.1000736. Epub 2009 Nov 20.
Abstract
摘要
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RNA-silencing enzymes Pol IV and Pol V in maize: more than one flavor?玉米中的RNA沉默酶Pol IV和Pol V：不止一种类型？
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Diversity of Pol IV function is defined by mutations at the maize rmr7 locus.Pol IV 功能的多样性是由玉米 rmr7 基因座的突变定义的。
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NRPD4, a protein related to the RPB4 subunit of RNA polymerase II, is a component of RNA polymerases IV and V and is required for RNA-directed DNA methylation.NRPD4是一种与RNA聚合酶II的RPB4亚基相关的蛋白质，是RNA聚合酶IV和V的一个组成部分，是RNA指导的DNA甲基化所必需的。
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Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II.RNA沉默酶Pol IV和Pol V的亚基组成揭示了它们作为RNA聚合酶II特殊形式的起源。
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Genetics of mutagenesis in E. coli: various combinations of translesion polymerases (Pol II, IV and V) deal with lesion/sequence context diversity.大肠杆菌中诱变的遗传学：跨损伤聚合酶（Pol II、IV和V）的各种组合应对损伤/序列背景多样性。
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本文引用的文献
1
Diversity of Pol IV function is defined by mutations at the maize rmr7 locus.Pol IV 功能的多样性是由玉米 rmr7 基因座的突变定义的。
PLoS Genet. 2009 Nov;5(11):e1000706. doi: 10.1371/journal.pgen.1000706. Epub 2009 Nov 20.
2
A dominant mutation in mediator of paramutation2, one of three second-largest subunits of a plant-specific RNA polymerase, disrupts multiple siRNA silencing processes.在植物特异性 RNA 聚合酶三个第二大亚基之一的表观遗传修饰调控因子 2 中，一个显性突变破坏了多个 siRNA 沉默过程。
PLoS Genet. 2009 Nov;5(11):e1000725. doi: 10.1371/journal.pgen.1000725. Epub 2009 Nov 20.
3
Production and processing of siRNA precursor transcripts from the highly repetitive maize genome.来自高度重复的玉米基因组的小干扰RNA前体转录本的产生与加工。
PLoS Genet. 2009 Aug;5(8):e1000598. doi: 10.1371/journal.pgen.1000598. Epub 2009 Aug 14.
4
RNA polymerase V transcription guides ARGONAUTE4 to chromatin.RNA聚合酶V转录将AGO4引导至染色质。
Nat Genet. 2009 May;41(5):630-4. doi: 10.1038/ng.365. Epub 2009 Apr 19.
5
RNA polymerase IV functions in paramutation in Zea mays.RNA聚合酶IV在玉米的副突变中发挥作用。
Science. 2009 Feb 27;323(5918):1201-5. doi: 10.1126/science.1164508.
6
RNA-mediated chromatin-based silencing in plants.植物中基于染色质的RNA介导的沉默
Curr Opin Cell Biol. 2009 Jun;21(3):367-76. doi: 10.1016/j.ceb.2009.01.025. Epub 2009 Feb 23.
7
Prion protein misfolding and disease.朊病毒蛋白错误折叠与疾病。
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8
Metal A and metal B sites of nuclear RNA polymerases Pol IV and Pol V are required for siRNA-dependent DNA methylation and gene silencing.核RNA聚合酶Pol IV和Pol V的金属A和金属B位点是小干扰RNA（siRNA）依赖的DNA甲基化和基因沉默所必需的。
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9
Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II.RNA沉默酶Pol IV和Pol V的亚基组成揭示了它们作为RNA聚合酶II特殊形式的起源。
Mol Cell. 2009 Jan 30;33(2):192-203. doi: 10.1016/j.molcel.2008.12.015. Epub 2008 Dec 24.
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Noncoding transcription by RNA polymerase Pol IVb/Pol V mediates transcriptional silencing of overlapping and adjacent genes.RNA聚合酶Pol IVb/Pol V介导的非编码转录调控重叠基因和相邻基因的转录沉默。
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