Allcock Darren M, Gardner Michael J, Sowers James R
Division of Endocrinology, Department of Internal Medicine, University of Missouri, Columbia, MO 65212, USA.
Int J Pediatr Endocrinol. 2009;2009:108187. doi: 10.1155/2009/108187. Epub 2009 Oct 19.
The incidence of overweight and obesity is rising at an alarming pace in the pediatric population, just as in the adult population. The adult comorbidities associated with this risk factor are well-recognized and are being further elucidated continually. Additionally, we are gradually developing a better understanding of the risks of overweight and obesity among children while they are still young. However, there is now a growing body of evidence showing that childhood obesity not only leads all too frequently to adult obesity, but is in itself a risk factor for cardiometabolic syndrome and resultant cardiovascular risk in adulthood. If current trends continue, the problem of pediatric overweight and obesity will become of unmanageable proportions once these individuals reach adulthood. Future research efforts toward understanding this complex problem will need to focus on those overweight and obese children who later went on to change their metabolic course and become normal-weight adults.
与成人人群一样,超重和肥胖在儿科人群中的发生率正以惊人的速度上升。与这一风险因素相关的成人合并症已得到充分认识,并且仍在不断深入研究。此外,我们也在逐渐加深对儿童期超重和肥胖风险的认识。然而,现在越来越多的证据表明,儿童肥胖不仅常常导致成人肥胖,其本身也是成年人心血管代谢综合征及心血管疾病风险的一个危险因素。如果当前趋势持续下去,这些儿童成年后,儿科超重和肥胖问题将变得难以控制。未来针对理解这一复杂问题的研究工作需要聚焦于那些后来改变了代谢轨迹并成为正常体重成年人的超重和肥胖儿童。