Sundkvist G, Lindahl G, Koskinen P, Bolinder J
Department of Medicine, University of Lund, Malmö General Hospital, Sweden.
J Intern Med. 1991 Jan;229(1):61-6. doi: 10.1111/j.1365-2796.1991.tb00307.x.
Pancreatic autoantibodies were determined in 49 patients with Sjögren's syndrome and related to functional parameters. Pancreatic duct autoantibodies (PDA) were detected in the sera of three patients, and all showed abnormal exocrine pancreatic function. Islet cell antibodies (ICA) were not detected in the sera of the 49 patients, including two individuals with diabetes mellitus. In conclusion, PDA occur in patients with Sjögren's syndrome, and may be associated with exocrine pancreatic dysfunction.
对49例干燥综合征患者检测了胰腺自身抗体，并与功能参数进行关联分析。在3例患者血清中检测到胰管自身抗体（PDA），且所有患者均表现出胰腺外分泌功能异常。49例患者血清中均未检测到胰岛细胞抗体（ICA），其中包括2例糖尿病患者。总之，干燥综合征患者可出现PDA，且可能与胰腺外分泌功能障碍有关。
