Khodzhibekov M Kh
Med Radiol (Mosk). 1991;36(2):7-9.
Perfusion scintigraphy of the lungs has shown that a reverse direction of postural reactions of the pulmonary blood flow is observed in patients with mitral valvular disease: perfusion of the upper lung rather than the lower lung increases. It is accounted for by the action of gravitation on capillary hydrostatic pressure resulting in the localization of interstitial edema in pulmonary venous hypertension mainly in the lower lung, its microcirculatory bed being compressed and the blood flow redistributed to the opposite upper lung. Therefore successive perfusion scintigraphy of the lungs in the vertical position and in the lateral position with a RP administered twice, can serve as a sensitive test for diagnosis of interstitial lung edema in various pathological conditions.
肺部灌注闪烁扫描显示，二尖瓣疾病患者存在肺血流姿势反应的反向情况：上肺而非下肺的灌注增加。这是由于重力作用于毛细血管静水压，导致肺静脉高压时间质水肿主要位于下肺，其微循环床受压，血流重新分布至相对的上肺。因此，在垂直位和侧位两次注射放射性药物后连续进行肺部灌注闪烁扫描，可作为诊断各种病理状态下间质性肺水肿的敏感检查。
