CTX-M 型β-内酰胺酶的产生和大肠杆菌 K1 的毒力。
CTX-M beta-lactamase production and virulence of Escherichia coli K1.
机构信息
University of Auvergne, Clermont-Ferrand F-63001, France.
出版信息
Emerg Infect Dis. 2009 Dec;15(12):1988-90. doi: 10.3201/eid1512.090928.
Abstract
We report a patient with neonatal meningitis caused by a CTX-M-1-producing Escherichia coli K1 strain. The influence of CTX-M production on virulence was investigated in cell culture and a newborn mouse model of meningitis. CTX-M production had no influence on virulence but was a major factor in clinical outcome.
摘要
我们报告了一例由产 CTX-M-1 大肠杆菌 K1 株引起的新生儿脑膜炎患者。在细胞培养和新生鼠脑膜炎模型中，研究了 CTX-M 产生对毒力的影响。CTX-M 的产生对毒力没有影响，但却是临床结果的主要因素。
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