Laboratory Department Naval Medical Center Portsmouth, Portsmouth, VA 23708, USA.
Hum Pathol. 2010 Feb;41(2):297-301. doi: 10.1016/j.humpath.2009.07.025. Epub 2009 Dec 4.
Rosai-Dorfman disease (also known as sinus histiocytosis with massive lymphadenopathy) is a rare disease of unknown etiology that typically presents as nodal disease in young children. However, it also can present in various extranodal sites and can be difficult to recognize if not considered in the differential diagnosis. We describe a 55-year-old man who was discovered to have extranodal Rosai-Dorfman disease that presented as a cardiac mass involving the left atrium and ventricle during evaluation for atypical chest pain, and discuss the clinical, radiologic, and pathologic findings as well as treatment approach and consideration of a possible relationship of this entity to IgG4-related sclerosing lesions.
罗萨达-多夫曼病（也称为伴有巨大淋巴结病的窦组织细胞增生症）是一种病因不明的罕见疾病，通常表现为年轻儿童的淋巴结疾病。然而，如果不在鉴别诊断中考虑，它也可能出现在各种结外部位，并且难以识别。我们描述了一名 55 岁男性，他在因非典型胸痛进行评估时被发现患有左心房和左心室的心脏肿块，这是一种结外罗萨达-多夫曼病，讨论了临床、放射学和病理学发现以及治疗方法，并考虑了这种实体与 IgG4 相关硬化病变的可能关系。
