Hôpital Cardiologique du Haut-Lévêque and Université Victor Segalen Bordeaux II, Bordeaux, France.
Heart Rhythm. 2010 Jan;7(1):2-8. doi: 10.1016/j.hrthm.2009.09.067. Epub 2009 Oct 6.
Peri-mitral atrial flutter (PMFL) is commonly encountered in patients undergoing atrial fibrillation (AF) ablation.
The purpose of this study was to determine the electrophysiologic characteristics, procedural success, and medium-term outcomes in patients with PMFL.
The study consisted of 50 consecutive patients (45 men and 5 women, age 57 +/- 12 years) with PMFL following or during AF ablation. Of the 50 PMFLs, 24 occurred during AF ablation (16 at index ablation and 8 at repeat procedure for recurrent AF), and 26 developed during follow-up. Ablation of PMFL was performed by creating a linear lesion joining the mitral annulus to the left inferior pulmonary vein.
The incidence of PMFL was higher in patients with mitral isthmus (MI) ablation performed during AF ablation, prior to the development of PMFL, than in those in whom MI ablation was not performed (23% vs 8%, P = .04). Following the procedure, PMFL was more frequent in patients with prior MI ablation than in those without (41% vs 15%, P <.01). Seventy percent (35/50) were terminated by ablation with 6.4 +/- 6.9 minutes of radiofrequency application. Among patients in whom PMFL terminated, supplemental ablation was required for bidirectional conduction block in 66% (23/35). MI block was achieved in 92% (46/50) using 13.6 +/- 7.4 minutes of ablation. At mean follow-up of 19 +/- 4 months, 96% of patients were free from PMFL.
PMFL can be terminated by MI ablation, but the procedure is proarrhythmic. Supplemental ablation is necessary to establish bidirectional block of the line despite termination of PMFL in the majority of patients.
二尖瓣环旁房扑(PMFL)在接受房颤(AF)消融的患者中较为常见。
本研究旨在确定 PMFL 患者的电生理特征、程序成功率和中期结果。
该研究包括 50 例连续的 PMFL 患者(45 名男性和 5 名女性,年龄 57 ± 12 岁),这些患者在 AF 消融过程中或之后出现 PMFL。50 例 PMFL 中,24 例发生在 AF 消融期间(16 例在指数消融时,8 例在复发性 AF 的重复手术时),26 例在随访期间发生。PMFL 的消融通过创建一条连接二尖瓣环和左下肺静脉的线性病变来完成。
在 AF 消融过程中或 PMFL 发生之前进行二尖瓣峡部消融的患者中,PMFL 的发生率高于未进行 MI 消融的患者(23% vs 8%,P =.04)。在手术后,有 MI 消融史的患者比没有 MI 消融史的患者更频繁地发生 PMFL(41% vs 15%,P <.01)。70%(35/50)的患者通过消融终止 PMFL,应用射频 6.4 ± 6.9 分钟。在 PMFL 终止的患者中,66%(23/35)需要补充消融以实现双向传导阻滞。92%(46/50)的患者通过消融实现 MI 阻滞,应用 13.6 ± 7.4 分钟。在平均 19 ± 4 个月的随访中,96%的患者无 PMFL。
MI 消融可终止 PMFL,但该操作具有致心律失常性。尽管大多数患者的 PMFL 终止,但仍需补充消融以建立线的双向阻滞。