Sprouse C, Yuh D, Abraham T, Burlina P
Johns Hopkins University Applied Physics Lab, USA.
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:3649-52. doi: 10.1109/IEMBS.2009.5332519.
We address the problem of hemodynamic computational modeling in the left heart complex. The novelty of our approach lies in the exploitation of prior patient specific data resulting from image analysis of Transesophageal Echocardiographic Imagery (TEE). Kinematic and anatomical information in the form of left heart chambers and valve boundaries is recovered through a level-set-based user-in-the-loop segmentation on 2D TEE. The resulting boundaries in the TEE sequence are then interpolated to prescribe the motion displacements in a computational fluid dynamics (CFD) model implemented using Finite Element Modeling (FEM) applied on Arbitrary Lagrangian-Eulerian (ALE) meshes. Experimental results are presented.
我们研究了左心复合体血流动力学计算建模的问题。我们方法的新颖之处在于利用经食管超声心动图成像（TEE）图像分析得到的患者特定先验数据。通过基于水平集的人工干预分割在二维TEE上恢复左心腔和瓣膜边界形式的运动学和解剖学信息。然后对TEE序列中得到的边界进行插值，以规定在使用有限元建模（FEM）应用于任意拉格朗日-欧拉（ALE）网格实现的计算流体动力学（CFD）模型中的运动位移。给出了实验结果。
