MR imaging in the differential diagnosis of scrotal and testicular disease.

It is frequently impossible to discriminate between various causes of scrotal pain and swelling by means of clinical examination and ultrasound (US) alone. Surgical exploration is necessary in cases of indefinite differential diagnosis. For evaluation of the diagnostic potential of magnetic resonance (MR) imaging in scrotal disease, 200 patients with testicular abnormalities were studied. For 74 of these patients, the diagnosis was cancer, based on clinical and US findings. MR imaging demonstrated malignant disease in 54 patients and benign disease in 20. All of the MR imaging findings were confirmed at surgical biopsy. Despite high costs of the procedure, the authors believe that MR imaging is a useful aid for diagnosis in cases of indefinite findings in scrotal and testicular disease.