Basu Sagar, Sanyal Debasish, Ghosal Malay, Roy Biman, Senapati A K, Das S K
Bangur Institute of Neurosciences and Psychiatry, Kolkata - 700 025, India.
Ann Indian Acad Neurol. 2008 Jan;11(1):28-32. doi: 10.4103/0972-2327.40222.
Assessment of Quality of Life in Epilepsy has currently been emphasized to provide comprehensive care to patients.
To develop and standardize and assess the psychometric properties of Bengali version of QOLIE-10 and to assess the relationship of quality of life with seizure variables and presence of psychiatric morbidity.
English QOLIE-10 was translated into Bengali by a translation committee using translation-re-translation technique. Inter-rater reliability between the English and Bengali version was assessed during initial practice session held amongst 20 bilingual patients. It was found that item 3 (related to driving) was reported to have difficulty in answering by all the patients as none drove any vehicle. Thus, this item was dropped. The inter-rater reliability of the resultant 9 item scale was found to be high (kappa = 0.9). One hundred and seven epilepsy patients attending the Epilepsy clinic were selected for the study if they met the following criteria: age >15 years, duration of seizure >1 year, regular intake of antiepileptic drugs, presence of informant and ability to read Bengali. For each patient, demographic and clinical data (seizure frequency, last seizure date, seizure type as per record, medicine intake history and records of past investigations such as EEG) was collected. Each patient were administered QOLIE-9 (Bengali) and SRQ-24 Bengali version to screen for psychiatric morbidity.
The Cronbach's Alpha coefficient for QOLIE-9 was 0.81, which did not improve if any item was dropped. All items showed strong correlation with the total score. The instrument showed stable factor structure with three factors (Limitation, Depression, Illness effects). However, the item with regard to memory problem did not fit into any of the factors. The QOLIE-9 total showed a significant correlation with the seizure frequency (r = 0.76**). SRQ positive (i.e., suspected psychiatric morbidity) cases had higher QOLIE-9 score (thus, poorer quality of life) in comparison to non-psychiatric cases.
Bengali QOLIE-9 is a valid and reliable instrument to assess the quality of life in patients suffering from epilepsy.
目前已强调对癫痫患者生活质量进行评估，以便为患者提供全面护理。
开发并标准化孟加拉语版QOLIE - 10，评估其心理测量特性，并评估生活质量与癫痫发作变量及精神疾病发病率之间的关系。
由一个翻译委员会采用翻译 - 再翻译技术将英语版QOLIE - 10翻译成孟加拉语。在20名双语患者参加的初始实践环节中评估英语版和孟加拉语版之间的评分者间信度。发现第3项（与驾驶有关）所有患者都表示难以回答，因为没有人开车。因此，该项目被删除。结果得到的9项量表的评分者间信度较高（kappa = 0.9）。如果癫痫门诊的107名癫痫患者符合以下标准，则被选入研究：年龄>15岁，癫痫发作持续时间>1年，规律服用抗癫痫药物，有 informant 且有能力阅读孟加拉语。为每位患者收集人口统计学和临床数据（癫痫发作频率、最后一次发作日期、记录的癫痫发作类型、用药史以及过去检查如脑电图的记录）。每位患者接受孟加拉语版QOLIE - 9和SRQ - 24以筛查精神疾病发病率。
QOLIE - 9的Cronbach's Alpha系数为0.81，删除任何项目后该系数都没有改善。所有项目与总分都显示出强相关性。该工具显示出稳定的因子结构，有三个因子（限制、抑郁、疾病影响）。然而，关于记忆问题的项目不符合任何一个因子。QOLIE - 9总分与癫痫发作频率显著相关（r = 0.76**）。与非精神疾病病例相比，SRQ阳性（即疑似精神疾病发病率）病例的QOLIE - 9得分更高（因此生活质量更差）。
孟加拉语版QOLIE - 9是评估癫痫患者生活质量的有效且可靠的工具。
