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Gadolinium-conjugated dendrimer nanoclusters as a tumor-targeted T1 magnetic resonance imaging contrast agent.

作者信息

Cheng Zhiliang, Thorek Daniel L J, Tsourkas Andrew

机构信息

Department of Bioengineering, University of Pennsylvania, 210 South 33rd Street, 240 Skirkanich Hall, Philadelphia, PA 19104, USA.

出版信息

Angew Chem Int Ed Engl. 2010;49(2):346-50. doi: 10.1002/anie.200905133.

DOI:10.1002/anie.200905133
PMID:19967688
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2862691/
Abstract
摘要

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1
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Acc Chem Res. 2009 Jul 21;42(7):893-903. doi: 10.1021/ar800245h.
2
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Contrast Media Mol Imaging. 2009 Mar-Apr;4(2):89-100. doi: 10.1002/cmmi.267.
3
Paramagnetic liposomes as innovative contrast agents for magnetic resonance (MR) molecular imaging applications.
Dendroids, Discrete Covalently Cross-Linked Dendrimer Superstructures.
树突状结构，离散共价交联树突状超结构。
ACS Nano. 2021 Jan 26;15(1):1666-1674. doi: 10.1021/acsnano.0c09322. Epub 2021 Jan 7.
4
A nephrotoxicity-free, iron-based contrast agent for magnetic resonance imaging of tumors.一种用于肿瘤磁共振成像的无肾毒性铁基造影剂。
Biomaterials. 2020 Oct;257:120234. doi: 10.1016/j.biomaterials.2020.120234. Epub 2020 Jul 15.
5
Glucosamine Conjugated Gadolinium (III) Oxide Nanoparticles as a Novel Targeted Contrast Agent for Cancer Diagnosis in MRI.葡萄糖胺共轭氧化钆（III）纳米颗粒作为一种用于MRI癌症诊断的新型靶向造影剂
J Biomed Phys Eng. 2020 Feb 1;10(1):25-38. doi: 10.31661/jbpe.v0i0.1018. eCollection 2020 Feb.
6
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7
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4
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Eur J Pharm Biopharm. 2009 Jun;72(2):397-404. doi: 10.1016/j.ejpb.2008.09.017. Epub 2008 Oct 10.
5
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Int J Nanomedicine. 2008;3(2):201-10.
6
Paramagnetic porous polymersomes.顺磁性多孔聚合物囊泡
Langmuir. 2008 Aug 5;24(15):8169-73. doi: 10.1021/la801027q. Epub 2008 Jun 21.
7
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8
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9
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10
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