百年洞察肠道微生物组！

A hundred-year-old insight into the gut microbiome!

机构信息

Department of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt.

出版信息

Gut Pathog. 2009 Dec 7;1(1):21. doi: 10.1186/1757-4749-1-21.

DOI:10.1186/1757-4749-1-21

PMID:19968883

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2797815/

Abstract

As the National Institutes of Health-funded Human Microbiome Project enters its second phase, and as a major part of this project focuses on the human gut microbiome and its effects on human health, it might help us to travel a century back in time and examine how microbiologists dealt with microbiome-related challenges similar to those of the 21st century using the tools of their time. An article by Arthur I. Kendall, published in The Journal of Biological Chemistry in November 1909 (Some observations on the study of the intestinal bacteria J Biol Chem 1909, 6:499-507), offers a visionary insight into many of today's hot research questions.

摘要

随着美国国立卫生研究院（NIH）资助的人类微生物组计划进入第二阶段，该计划的一个主要部分集中在人类肠道微生物组及其对人类健康的影响上，我们或许可以回到一个世纪前，利用当时的工具，研究微生物学家如何应对类似于 21 世纪的与微生物组相关的挑战。亚瑟·I·肯德尔（Arthur I. Kendall）于 1909 年 11 月在《生物化学杂志》（The Journal of Biological Chemistry）上发表的一篇文章（《关于肠道细菌研究的一些观察》，Some observations on the study of the intestinal bacteria J Biol Chem 1909, 6:499-507），为当今许多热门研究问题提供了具有远见的见解。