肠道病原体：复杂宇宙中的侵略者和叛徒。
Gut pathogens: invaders and turncoats in a complex cosmos.
机构信息
Division of Nutritional Sciences, Franklin-Wilkins Building, King's College London, Stamford Street, London SE1 9NH, UK.
出版信息
Gut Pathog. 2009 Feb 3;1(1):3. doi: 10.1186/1757-4749-1-3.
Abstract
Intestinal infections and diarrhoeal diseases of humans are under-reported yet each account worldwide for more deaths than those from Tuberculosis. For external gut pathogens to do this they have to penetrate, survive and prosper in an established and defended ecosystem comprising the human gut with a massive immune system, a structured tight mucosal lining and a lumen densely occupied by a huge community of diverse bacteria adapted to their environment and optimised in a balanced and mutually beneficial relationship with its host.
摘要
人类的肠道感染和腹泻病报告不足，但全球每例此类疾病的死亡人数都超过了结核病。为了做到这一点，外部肠道病原体必须穿透、存活并在一个由人类肠道组成的既定和受保护的生态系统中繁荣发展，这个生态系统拥有庞大的免疫系统、结构紧密的黏膜内层和充满大量适应其环境并与其宿主保持平衡互利关系的多样化细菌的腔室。
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