深部脑刺激治疗运动障碍。

Deep brain stimulation for movement disorders.

机构信息

Department of Neurosurgery, University of Michigan Medical Center, 1500 E. Medical Center Drive, SPC 5338, Ann Arbor, MI 48109-5338, USA.

出版信息

Neurobiol Dis. 2010 Jun;38(3):338-45. doi: 10.1016/j.nbd.2009.11.019. Epub 2009 Dec 5.

DOI:10.1016/j.nbd.2009.11.019

PMID:19969083

Abstract

Deep brain stimulation (DBS) is a widely employed therapeutic modality for the treatment of movement disorders. Full FDA approval or humanitarian device exemption has been made for Parkinson's disease, tremor, and dystonia. In this review, we describe the indications and selection criteria, target selection, and outcomes for each of these conditions. In addition, we describe the operative techniques utilized in DBS surgery and look forward to new developments in DBS on the horizon.

摘要

脑深部电刺激（DBS）是一种广泛应用于治疗运动障碍的治疗方法。帕金森病、震颤和肌张力障碍已获得 FDA 全面批准或人道主义设备豁免。在这篇综述中，我们描述了这些疾病的适应证和选择标准、靶点选择和结果。此外，我们还描述了 DBS 手术中使用的手术技术，并展望了 DBS 的新发展。