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认知障碍对多发性硬化症应对策略的影响。

Impact of cognitive impairment on coping strategies in multiple sclerosis.

作者信息

Goretti Benedetta, Portaccio Emilio, Zipoli Valentina, Hakiki Bahia, Siracusa Gianfranco, Sorbi Sandro, Amato Maria Pia

机构信息

Department of Neurology, University of Florence, Italy.

出版信息

Clin Neurol Neurosurg. 2010 Feb;112(2):127-30. doi: 10.1016/j.clineuro.2009.10.019. Epub 2009 Dec 6.

Abstract

OBJECTIVES

To assess the impact of cognitive impairment (CI) on coping strategies in multiple sclerosis (MS).

MATERIALS AND METHODS

Sixty-three patients (40 women, 55 relapsing-remitting and 8 secondary progressive, age 42.6+/-10.1 years, Expanded Disability Status Scale 2.2+/-1.7) were assessed using the Coping Orientation for Problem Experiences-New Italian version Inventory, the Beck Depression Inventory and the Rao's Brief Repeatable Battery.

RESULTS

MS patients were less likely to use positive and problem-focused strategies, whereas avoiding strategies were adopted more frequently. Twenty-three (36.5%) cases were CI. We found no differences in the type of coping between CI and cognitively preserved patients. Scores on the Stroop test (beta=-0.91, p=0.04) and on the Word List Generation (beta=1.15, p=0.04) were associated with poorer coping strategies.

CONCLUSIONS

Our study suggests that cognitive functioning (in particular on sustained attention and aspects of executive function) must be considered in a comprehensive account of the factors contributing to successful coping in MS patients.

摘要

目的

评估认知障碍(CI)对多发性硬化症(MS)应对策略的影响。

材料与方法

使用问题体验应对取向新意大利版量表、贝克抑郁量表和拉奥简易重复性成套测验对63例患者(40名女性,55例复发缓解型和8例继发进展型,年龄42.6±10.1岁,扩展残疾状态量表评分2.2±1.7)进行评估。

结果

MS患者较少使用积极和以问题为中心的策略,而更多采用回避策略。23例(36.5%)存在CI。我们发现CI患者和认知功能正常患者在应对方式上没有差异。斯特鲁普测验得分(β=-0.91,p=0.04)和词语流畅性测验得分(β=1.15,p=0.04)与较差的应对策略相关。

结论

我们的研究表明,在全面考虑影响MS患者成功应对的因素时,必须考虑认知功能(特别是持续注意力和执行功能方面)。

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