Goretti Benedetta, Portaccio Emilio, Zipoli Valentina, Hakiki Bahia, Siracusa Gianfranco, Sorbi Sandro, Amato Maria Pia
Department of Neurology, University of Florence, Italy.
Clin Neurol Neurosurg. 2010 Feb;112(2):127-30. doi: 10.1016/j.clineuro.2009.10.019. Epub 2009 Dec 6.
To assess the impact of cognitive impairment (CI) on coping strategies in multiple sclerosis (MS).
Sixty-three patients (40 women, 55 relapsing-remitting and 8 secondary progressive, age 42.6+/-10.1 years, Expanded Disability Status Scale 2.2+/-1.7) were assessed using the Coping Orientation for Problem Experiences-New Italian version Inventory, the Beck Depression Inventory and the Rao's Brief Repeatable Battery.
MS patients were less likely to use positive and problem-focused strategies, whereas avoiding strategies were adopted more frequently. Twenty-three (36.5%) cases were CI. We found no differences in the type of coping between CI and cognitively preserved patients. Scores on the Stroop test (beta=-0.91, p=0.04) and on the Word List Generation (beta=1.15, p=0.04) were associated with poorer coping strategies.
Our study suggests that cognitive functioning (in particular on sustained attention and aspects of executive function) must be considered in a comprehensive account of the factors contributing to successful coping in MS patients.
评估认知障碍（CI）对多发性硬化症（MS）应对策略的影响。
使用问题体验应对取向新意大利版量表、贝克抑郁量表和拉奥简易重复性成套测验对63例患者（40名女性，55例复发缓解型和8例继发进展型，年龄42.6±10.1岁，扩展残疾状态量表评分2.2±1.7）进行评估。
MS患者较少使用积极和以问题为中心的策略，而更多采用回避策略。23例（36.5%）存在CI。我们发现CI患者和认知功能正常患者在应对方式上没有差异。斯特鲁普测验得分（β=-0.91，p=0.04）和词语流畅性测验得分（β=1.15，p=0.04）与较差的应对策略相关。
我们的研究表明，在全面考虑影响MS患者成功应对的因素时，必须考虑认知功能（特别是持续注意力和执行功能方面）。
