Culicetto Laura, Lo Buono Viviana, Donato Sofia, La Tona Antonino, Cusumano Anita Maria Sophia, Corello Graziana Marika, Sessa Edoardo, Rifici Carmela, D'Aleo Giangaetano, Quartarone Angelo, Marino Silvia
IRCCS Centro Neurolesi "Bonino-Pulejo", S.S. 113 Via Palermo C. da Casazza, 98124 Messina, Italy.
Department of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.
J Clin Med. 2024 Sep 18;13(18):5505. doi: 10.3390/jcm13185505.
Multiple sclerosis (MS) is a neurodegenerative disorder of the central nervous system characterized by a variety of symptoms such as fatigue, spasticity, tremors, and cognitive disorders. Individuals with MS may employ different coping strategies to manage these symptoms, which in turn can significantly impact their quality of life (QoL). This review aims to analyze these coping strategies and their impact on QoL. Furthermore, it seeks to identify the key factors that influence the choice and effectiveness of these coping strategies, providing insights into which strategies are most beneficial for enhancing QoL in people with MS. Systematic searches were performed in Scopus, PubMed, Web of Science, and Scopus databases. This systematic review has been registered in OSF with the number DOI 10.17605/OSF.IO/QY37X. : A total of 1192 studies were identified. After reading the full text of the selected studies and applying predefined inclusion criteria, 19 studies were included based on their pertinence and relevance to the topic. The results revealed that emotional variables, demographic factors, personality traits, and family support significantly influence the choice of coping strategies used to manage the symptoms of MS. Problem-solving and task-oriented coping were prevalent among MS patients and associated with better QoL outcomes. Emotional-focused and avoidance strategies were generally linked to poorer QoL, though avoidance provided temporary relief in certain contexts. Social support, emotional health, and cognitive reframing were crucial in enhancing QoL. : The findings underscore the importance of tailored psychoeducational and therapeutic interventions focusing on emotional health, social support, and adaptive coping strategies. These interventions can significantly improve the long-term outcomes for individuals with MS. Future research should explore the dynamic interactions between coping strategies and QoL over time, providing a comprehensive understanding of how to best support MS patients in managing their disease.
多发性硬化症（MS）是一种中枢神经系统的神经退行性疾病，其特征表现为多种症状，如疲劳、痉挛、震颤和认知障碍。患有MS的个体可能会采用不同的应对策略来管理这些症状，而这些策略反过来又会对他们的生活质量（QoL）产生重大影响。本综述旨在分析这些应对策略及其对生活质量的影响。此外，它还试图确定影响这些应对策略选择和有效性的关键因素，从而深入了解哪些策略对提高MS患者的生活质量最为有益。我们在Scopus、PubMed、Web of Science和Scopus数据库中进行了系统检索。本系统综述已在开放科学框架（OSF）上注册，编号为DOI 10.17605/OSF.IO/QY37X。共识别出1192项研究。在阅读所选研究的全文并应用预定义的纳入标准后，基于其与主题的相关性，纳入了19项研究。结果显示，情绪变量、人口统计学因素、人格特质和家庭支持显著影响用于管理MS症状的应对策略的选择。解决问题和任务导向型应对在MS患者中很普遍，并且与更好的生活质量结果相关。情绪聚焦和回避策略通常与较差的生活质量相关，不过在某些情况下回避能提供暂时缓解。社会支持、情绪健康和认知重构对于提高生活质量至关重要。研究结果强调了针对情绪健康、社会支持和适应性应对策略的量身定制的心理教育和治疗干预措施的重要性。这些干预措施可以显著改善MS患者的长期预后。未来的研究应探索应对策略与生活质量随时间的动态相互作用，以便全面了解如何最好地支持MS患者管理他们的疾病。
