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颅内视神经结节病样病变

Sarcoid-like disorder of the intracranial optic nerve.

作者信息

Frisén L, Lindgren S, MacGregor B J, Stattin S

出版信息

J Neurol Neurosurg Psychiatry. 1977 Jul;40(7):702-7. doi: 10.1136/jnnp.40.7.702.

Abstract

Two cases with a sarcoid-like disorder apparently restricted to the intracranial optic nerve and the adjacent dura mater are described, doublilng the number of reported cases. In both instances there were unilateral visual loss and unusual radiographic changes in the optic canal area. Biopsy samples showed localised infiltration of tissues with non-caseating tubercles containing epithelioid and multinucleated giant cells.

摘要

本文描述了两例类肉瘤样疾病,病变显然局限于颅内视神经及相邻硬脑膜,使报告病例数增加了一倍。两例均有单侧视力丧失及视神经管区域异常影像学改变。活检样本显示,组织中有局灶性浸润,存在含上皮样细胞和多核巨细胞的非干酪样结节。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7498/492808/d2b5c9d65027/jnnpsyc00157-0079-a.jpg

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