Greer S, Moorey S, Baruch J
Cancer Research Campaign Psychological Medicine Group, Royal Marsden Hospital, Sutton, Surrey, UK.
Br J Cancer. 1991 Feb;63(2):257-60. doi: 10.1038/bjc.1991.60.
Adjuvant psychological therapy (APT) is a newly developed cognitive behavioural treatment which has been designed specifically to improve the quality of life of cancer patients by alleviating emotional distress and inducing a fighting spirit. We report a phase I/II study which evaluates APT in routine clinical practice. A consecutive series of 44 outpatients with various cancers referred for psychiatric consultation and receiving APT at the Royal Marsden Hospital was studied. Standardised self-report questionnaires were used to measure anxiety, depression and four principal categories of mental adjustment to cancer, namely, fighting spirit, helplessness, anxious preoccupation and fatalism. Statistical comparisons between pre-therapy scores and scores after an average of five APT sessions revealed significant improvement in anxiety, depression, fighting spirit, anxious preoccupation and helplessness. Fatalism scores showed the same trend, but the changes were smaller. Patients with advanced disease showed as much improvement as those with local or locoregional disease. Present results indicate improvement in both psychiatric symptoms and mental adjustment to cancer associated with APT. Whether this association is causal remains to be determined by randomised controlled trials. Such a trial is in progress.
辅助心理治疗(APT)是一种新开发的认知行为疗法,专门设计用于通过减轻情绪困扰和激发斗志来提高癌症患者的生活质量。我们报告了一项在常规临床实践中评估APT的I/II期研究。对皇家马斯登医院连续44例因精神科会诊而接受APT治疗的各类癌症门诊患者进行了研究。使用标准化的自我报告问卷来测量焦虑、抑郁以及对癌症心理调适的四个主要类别,即斗志、无助感、焦虑专注和宿命论。治疗前分数与平均五次APT治疗后的分数之间的统计比较显示,焦虑、抑郁、斗志、焦虑专注和无助感均有显著改善。宿命论分数呈现相同趋势,但变化较小。晚期疾病患者与局部或区域疾病患者的改善程度相同。目前的结果表明,与APT相关的精神症状和对癌症的心理调适均有改善。这种关联是否具有因果关系仍有待随机对照试验来确定。这样的试验正在进行中。