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Adriamycin-induced neoplastic lesions in the Egyptian toad Bufo regularis.

作者信息

el-Mofty M M, Khudoley V V, Sakr S A, Osman S I, Toulan B A

机构信息

Department of Zoology, Faculty of Science, University of Alexandria, Egypt.

出版信息

Oncology. 1991;48(2):171-4. doi: 10.1159/000226920.

DOI:10.1159/000226920
PMID:1997943
Abstract

Injecting adult toads (Bufo regularis) subcutaneously in the dorsal lymph sac with adriamycin at a dose of 2 mg/kg body weight, once every 3 weeks for 20 weeks, induced hepatocellular carcinomas in 20 out of 100 animals. Metastases of the primary liver tumors appeared in the kidneys of 7 toads.

摘要

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