Hirsch G H, Menard M R, Anton H A
Department of Medicine, University Hospital-Shaughnessy, Vancouver, BC, Canada.
Arch Phys Med Rehabil. 1991 Mar;72(3):195-201.
The incidence and natural history of anemia in patients with spinal cord injuries (SCI) were investigated in a prospective study of 68 patients consecutively admitted to a regional acute SCI unit. Fifty had SCI and 18 had spine injuries (SI) without neurologic deficit. Thirty-six of 41 males (88%) and six of nine females (67%) with SCI were anemic on at least one occasion. In the first two weeks after injury, in females and in males, there was no significant difference in mean hemoglobin level between SI and SCI patients. At six weeks, no male with SI was anemic, and males with SCI had significantly lower mean hemoglobin levels than those with SI (121.6 g/L vs 145.4 g/L, p less than .001). Identified early causes of anemia were blood loss due to bony soft tissue or visceral injury, gastrointestinal bleeding, and surgery. In the postacute phase (more than six weeks after injury), anemia occurred in 25 of 41 male and three of nine female SCI patients, and its occurrence was associated with the presence of an identified chronic disease, especially urinary tract infection.
在一项对一家地区急性脊髓损伤（SCI）病房连续收治的68例患者进行的前瞻性研究中，调查了脊髓损伤患者贫血的发生率和自然病程。其中50例为脊髓损伤患者，18例为无神经功能缺损的脊柱损伤（SI）患者。41例男性脊髓损伤患者中有36例（88%）、9例女性脊髓损伤患者中有6例（67%）至少有一次出现贫血。在受伤后的前两周，无论男性还是女性，脊柱损伤患者和脊髓损伤患者的平均血红蛋白水平均无显著差异。在六周时，无脊柱损伤的男性无贫血，脊髓损伤男性的平均血红蛋白水平显著低于脊柱损伤男性（121.6 g/L对145.4 g/L，p<0.001）。已确定的贫血早期原因包括骨软组织或内脏损伤、胃肠道出血及手术导致的失血。在急性后期（受伤六周后），41例男性脊髓损伤患者中有25例、9例女性脊髓损伤患者中有3例出现贫血，其发生与已确诊的慢性病有关，尤其是尿路感染。
