Huang C T, DeVivo M J, Stover S L
Department of Rehabilitation Medicine, University of Alabama, Birmingham 35294.
Arch Phys Med Rehabil. 1990 Jan;71(1):3-7.
Anemia is a frequent complication during the acute phase of spinal cord injury (SCI), even in the absence of detectable blood loss. Since an improved understanding of the etiology of anemia in this population is a prerequisite to its ultimate prevention, a prospective study was conducted on 28 persons with SCI whose lesions were between C3 and C7. The injuries were either neurologically complete, incomplete with sensory sparing only, or incomplete with nonfunctional motor preservation. Laboratory profiles were obtained during the first few weeks postinjury. No persons had below-normal plasma volumes, while 9% had below-normal blood volumes. However, 82% had below-normal red cell masses, 25% had below-normal serum erythropoietin levels, and 11% had below-normal reticulocyte counts. Other below-normal values included erythrocyte count (75%), hemoglobin (79%), hematocrit (71%), mean corpuscular volume (11%), mean corpuscular hemoglobin (11%), serum iron (50%), total iron binding capacity (86%), iron saturation (50%), serum total protein (57%), serum albumin (89%), serum globulin (32%), and serum transferrin (79%). Most persons (71%) were found to have normochromic, normocytic anemia, although 14% had normochromic, microcytic anemia. Only 14% did not develop anemia. Although these cases of anemia were not severe enough to require transfusions, they might be an important factor in the development of other secondary complications and may combine with other nutritional and hematologic deficiencies to prolong the rehabilitation process.
贫血是脊髓损伤（SCI）急性期常见的并发症，即使在没有可检测到失血的情况下也是如此。由于更好地了解该人群贫血的病因是最终预防贫血的先决条件，因此对28例C3至C7节段损伤的脊髓损伤患者进行了一项前瞻性研究。损伤类型包括神经功能完全性损伤、仅保留感觉功能的不完全性损伤或保留无功能运动的不完全性损伤。在受伤后的头几周内进行了实验室检查。没有人的血浆量低于正常水平，而9%的人的血容量低于正常水平。然而，82%的人的红细胞量低于正常水平，25%的人的血清促红细胞生成素水平低于正常水平，11%的人的网织红细胞计数低于正常水平。其他低于正常水平的值包括红细胞计数（75%）、血红蛋白（79%）、血细胞比容（71%）、平均红细胞体积（11%）、平均红细胞血红蛋白含量（11%）、血清铁（50%）、总铁结合力（86%）、铁饱和度（50%）、血清总蛋白（57%）、血清白蛋白（89%）、血清球蛋白（32%）和血清转铁蛋白（79%）。大多数人（71%）被发现患有正色素性、正细胞性贫血，尽管14%的人患有正色素性、小细胞性贫血。只有14%的人没有发生贫血。尽管这些贫血病例并不严重到需要输血，但它们可能是其他继发性并发症发生的重要因素，并且可能与其他营养和血液学缺乏症合并，从而延长康复过程。
