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遗传性C5缺乏症与盘状红斑狼疮相关。

Hereditary deficiency of C5 in association with discoid lupus erythematosus.

作者信息

Asghar S S, Venneker G T, van Meegen M, Meinardi M M, Hulsmans R F, de Waal L P

机构信息

Department of Dermatology, Academic Medical Center, University of Amsterdam, The Netherlands.

出版信息

J Am Acad Dermatol. 1991 Feb;24(2 Pt 2):376-8. doi: 10.1016/0190-9622(91)70056-8.

DOI:10.1016/0190-9622(91)70056-8
PMID:1999552
Abstract

A 29-year-old woman with discoid lupus erythematosus had undetectable classic pathway complement activity. Hypocomplementemia was due to selective deficiency of C5. One of her children was also deficient. To our knowledge this is the first documented case of an association between discoid lupus erythematosus and C5 deficiency.

摘要

一名患有盘状红斑狼疮的29岁女性,其经典途径补体活性检测不到。补体血症是由于C5选择性缺乏所致。她的一个孩子也存在这种缺陷。据我们所知,这是首例有文献记载的盘状红斑狼疮与C5缺乏之间关联的病例。

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Hereditary deficiency of C5 in association with discoid lupus erythematosus.遗传性C5缺乏症与盘状红斑狼疮相关。
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