Psychiatrist, Pedro Hispano General Hospital, Department of Mental Health - Psychiatry Service, Rua Dr. Eduardo Torres, 4454-509 Matosinhos, Portugal.
J Neuropsychiatry Clin Neurosci. 2009 Fall;21(4):413-9. doi: 10.1176/jnp.2009.21.4.413.
Parkinson's disease has a major impact on quality of life. This cross-sectional study assessed 43 idiopathic Parkinson's disease patients in order to evaluate the impact of Parkinson's disease severity (Hoehn and Yahr scale), anxiety, and depression (Hospital Anxiety and Depression Scale) on quality of life (Short Form-36 Health Survey questionnaire). Hospital Anxiety and Depression Scale and Short Form-36 Health Survey scores were significantly correlated in Hoehn and Yahr stage 2 Parkinson's disease (n=33), and anxiety had a strong correlation with physical score. Multivariate analysis (n=43) revealed that anxiety was the strongest predictor of quality of life. Anxious and depressive symptoms have a different meaning in Parkinson's disease, and both must be routinely assessed in order to optimize quality of life.
帕金森病对生活质量有重大影响。本横断面研究评估了 43 例特发性帕金森病患者，以评估帕金森病严重程度（Hoehn 和 Yahr 量表）、焦虑和抑郁（医院焦虑和抑郁量表）对生活质量（36 项简短健康调查问卷）的影响。在 Hoehn 和 Yahr 2 期帕金森病患者（n=33）中，医院焦虑和抑郁量表和 36 项简短健康调查问卷评分显著相关，焦虑与生理评分呈强相关。多变量分析（n=43）显示，焦虑是生活质量的最强预测因子。焦虑和抑郁症状在帕金森病中有不同的意义，为了优化生活质量，必须常规评估这两种症状。
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