Nazli Rubina, Haider Jamila, Khan Mohammad Akmal, Akhtar Tasleem, Aslam Hina
Dr. Rubina Nazli, MBBS, PhD. Associate Professor of Biochemistry, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan.
Jamila Haider, BS (Microbiology), PhD Scholor. Centre of Biotechnology & Microbiology, University of Peshawar, Peshawar, Pakistan.
Pak J Med Sci. 2015 Jul-Aug;31(4):984-6. doi: 10.12669/pjms.314.6640.
To determine the frequency of ABO blood group and Rhesus (Rh) D antigen in the females of "District" Peshawar, Khyber Pakhtunkhwa Province, Pakistan.
This cross-sectional study was conducted on 429 women having pregnancy induced hypertension, admitted in the three teaching hospitals of Peshawar, over a period of one year. Blood sample was collected from each subject after taking informed consent. The antigen antibody agglutination slide test for "blood grouping (ABO)" and RhD factors was done by using IgM and IgG monoclonal reagents. The antisera used were from Biolaboratory, USA. Data was analyzed for percentage calculation.
The blood group distribution was 134 (31.2%), 43 (10.1%), 116 (27%), 136 (31.7%) for blood groups A, AB, O and B, respectively. Subjects having blood group B was slightly more dominant, followed by A and O, while blood group AB was rare in these females. Blood group A Rh negative is more in female 12 (37.5%) followed by group O 10 (31.3%), group B 09 (28.1%) and group AB 01 (3.1%).
Frequency of "Rh-positive blood group" is B, A, O and AB, whereas the frequency of the most common Rh-negative blood group are A, O, B and AB respectively. The determination of the frequency of blood groups in the region would not only help in blood transfusion services, but also reduce the risk of erythroblastosis foetalis in the neonates.
确定巴基斯坦开伯尔-普赫图赫瓦省白沙瓦市“地区”女性的ABO血型和恒河猴(Rh)D抗原频率。
本横断面研究对白沙瓦市三家教学医院收治的429例妊娠高血压女性进行了为期一年的研究。在获得知情同意后,从每位受试者采集血样。使用IgM和IgG单克隆试剂进行“血型(ABO)”和RhD因子的抗原抗体凝集玻片试验。所用抗血清来自美国生物实验室。对数据进行百分比计算分析。
A、AB、O和B血型的分布分别为134例(31.2%)、43例(10.1%)、116例(27%)、136例(31.7%)。B血型的受试者略占优势,其次是A和O,而AB血型在这些女性中很少见。A血型Rh阴性女性居多,有12例(37.5%),其次是O血型10例(31.3%)、B血型9例(28.1%)和AB血型1例(3.1%)。
“Rh阳性血型”的频率依次为B、A、O和AB,而最常见的Rh阴性血型频率依次为A、O、B和AB。确定该地区的血型频率不仅有助于输血服务,还能降低新生儿溶血病的风险。