Beliaeva I V
Vopr Med Khim. 1977 Jul-Aug;23(4):440-4.
Content of cholesterol, its esters, total beta-lipoproteins and free fatty acids was increased in blood serum of rats, subjected to thymectomia after birth. The distinct sex variations were found in alterations of these patterns. Content of cholesterol was increased only in thymectomized males at the age of 3 months; content of beta-lipoproteins in males was elevated earlier and to higher level as compared wtih females. Alteration in content of blood serum lipids did not depend on manifestations of exhaustion syndrome (typical consequence of neonatal thymectomia) but it was related to ablation of thymus; this suggests that thymus participates in regulation of lipid metabolism. Sex differences in alterations of lipid metabolism patterns enabled to assume the existence of endocrine interrelations between thymus and sex glands.
出生后接受胸腺切除的大鼠血清中胆固醇、其酯类、总β-脂蛋白和游离脂肪酸的含量增加。在这些模式的变化中发现了明显的性别差异。仅在3个月大的胸腺切除雄性大鼠中胆固醇含量增加；与雌性相比，雄性β-脂蛋白含量升高更早且更高。血清脂质含量的变化不取决于衰竭综合征（新生儿胸腺切除的典型后果）的表现，而是与胸腺切除有关；这表明胸腺参与脂质代谢的调节。脂质代谢模式变化中的性别差异使人们能够推测胸腺与性腺之间存在内分泌相互关系。
