Columbia University Medical Center, Ophthalmology, New York 10032, USA.
Ocul Immunol Inflamm. 2009 Nov-Dec;17(6):400-2. doi: 10.3109/09273940903118634.
To demonstrate that fundus autofluorescence (FAF) imaging aides the diagnosis of rubella retinopathy (RR).
Four patients with sensorineural hearing loss underwent ophthalmic exams, electro-retinogram testing (ERG), and FAF in both eyes. Fluorescein angiogram (FA) was performed in one case.
Salt-and-pepper retinopathy was observed in seven eyes. FAF highlighted the fundus abnormalities with stippled fluorescence in all seven eyes. ERG showed normal retinal function in all eyes. Choroidal neovascularization was identified by FA in one eye.
FAF is sensitive to the retinal pigment epithelium disturbance caused by rubella and noninvasively helps establish the diagnosis of RR.
证明眼底自发荧光(FAF)成像有助于风疹视网膜病变(RR)的诊断。
对 4 名患有感觉神经性听力损失的患者进行了眼科检查、视网膜电图(ERG)检查以及双眼 FAF。对 1 例患者进行了荧光素血管造影(FA)检查。
7 只眼观察到椒盐状视网膜病变。FAF 使所有 7 只眼的眼底异常呈点状荧光。ERG 显示所有眼的视网膜功能正常。1 只眼通过 FA 发现脉络膜新生血管。
FAF 对风疹引起的视网膜色素上皮紊乱敏感,可无创性帮助确立 RR 的诊断。