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不同严重程度特应性皮炎患者皮肤中产麦角固醇的马拉色菌菌群的分子分析。

Molecular analysis of the cutaneous Malassezia microbiota from the skin of patients with atopic dermatitis of different severities.

机构信息

Department of Dermatology, Juntendo University, School of Medicine, Tokyo, Japan.

出版信息

Mycoses. 2011 Jul;54(4):e24-8. doi: 10.1111/j.1439-0507.2009.01821.x. Epub 2009 Dec 11.

Abstract

Cutaneous Malassezia is an exacerbating factor in patients with atopic dermatitis. We analysed the Malassezia microbiota of adult patients with head and neck atopic dermatitis of different severities (mild, moderate and severe). Of the nine human-associated Malassezia species, the number detected was similar (3.5-4.2 species per case) among the members of all severity groups. However, the ratio of the two major Malassezia species, M. globosa and M. restricta, was different in the severe group.

摘要

皮肤马拉色菌是特应性皮炎患者的加重因素。我们分析了不同严重程度(轻度、中度和重度)的头颈部特应性皮炎成年患者的马拉色菌菌群。在 9 种与人类相关的马拉色菌物种中,所有严重程度组的病例中检测到的物种数量相似(每例 3.5-4.2 种)。然而,在严重组中,两种主要的马拉色菌物种即 M. globosa 和 M. restricta 的比例不同。

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