Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Japan.
Dermatology. 2010;221(3):253-60. doi: 10.1159/000320234.
Malassezia is a particularly important factor in the occurrence of atopic dermatitis (AD).
The aim of this study was to quantitatively clarify the Malassezia species isolated from AD patients by gender, body part and analytical method in detail.
The subjects were 20 AD males and 47 AD females. Samples were collected from lesion and nonlesion areas on the face and upper trunk of AD patients. Malassezia DNA was analyzed using a real-time PCR system.
The cutaneous Malassezia microbiota in AD patients differed by gender, body part and analytical method.
The present results indicate the possibility that the influence of Malassezia antigens is different according to gender and body part.
马拉色菌是特应性皮炎（AD）发生的一个特别重要的因素。
本研究旨在详细定量阐明通过性别、身体部位和分析方法从 AD 患者中分离出的马拉色菌种。
研究对象为 20 名男性 AD 患者和 47 名女性 AD 患者。采集 AD 患者面部和上躯干皮损和非皮损区域的样本。使用实时 PCR 系统分析马拉色菌 DNA。
AD 患者的皮肤马拉色菌菌群因性别、身体部位和分析方法而异。
本研究结果表明，马拉色菌抗原的影响可能因性别和身体部位而异。
