2nd Department of Ophthalmology, University of Athens, Greece.
Acta Ophthalmol. 2012 Feb;90(1):96-8. doi: 10.1111/j.1755-3768.2009.01745.x. Epub 2009 Dec 9.
To document and study the spontaneous closure of lamellar macular holes (LMH) by optical coherence tomography (OCT).
Two women with LMH, 62 and 71 years old, respectively, were followed up with fundoscopy, fundus photography and OCT.
In both patients spontaneous closure of LMH was observed 11 and 21 months after baseline examination, respectively. The foveal thickness in case 1 increased from 84 μm at baseline to 162 μm at the final examination. The foveal thickness in case 2 increased from 48 μm at baseline to 148 μm at the final examination. The foveal contour was also restored in both eyes. The foveal morphology was preserved in both eyes during the follow-up period.
In both patients the spontaneous closure of LMH could be attributed to the shrinkage of the hole or the release of the tension on the retinal surface, which followed the complete posterior vitreous detachment and separation of epiretinal membrane from the retina.
通过光学相干断层扫描(OCT)记录和研究板层黄斑裂孔(LMH)的自发闭合。
对两名分别为 62 岁和 71 岁的 LMH 女性患者进行眼底镜检查、眼底照相和 OCT 随访。
两名患者的 LMH 在基线检查后 11 个月和 21 个月分别自发闭合。第 1 例的黄斑中心凹厚度从基线时的 84μm增加到最后一次检查时的 162μm。第 2 例的黄斑中心凹厚度从基线时的 48μm增加到最后一次检查时的 148μm。在两只眼中,黄斑中心凹轮廓也得到了恢复。在随访期间,两只眼的黄斑形态均得到了保留。
在这两名患者中,LMH 的自发闭合可归因于孔的缩小或视网膜表面张力的释放,这是在完全玻璃体后脱离和视网膜内的内界膜与视网膜分离后发生的。